Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB   Type   Machinery gene
Locus tag   AB3423_RS08745 Genome accession   NZ_CP162461
Coordinates   1745460..1746530 (+) Length   356 a.a.
NCBI ID   WP_000776422.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM20913     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1740460..1751530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3423_RS08715 (AB3423_08715) - 1740883..1742346 (+) 1464 WP_001017865.1 rhomboid family intramembrane serine protease -
  AB3423_RS08720 (AB3423_08720) - 1742327..1742530 (+) 204 WP_000087561.1 YqgQ family protein -
  AB3423_RS08725 (AB3423_08725) - 1742527..1743513 (+) 987 WP_000161314.1 ROK family glucokinase -
  AB3423_RS08730 (AB3423_08730) - 1743513..1743842 (+) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  AB3423_RS08735 (AB3423_08735) - 1743839..1744462 (+) 624 WP_001223010.1 MBL fold metallo-hydrolase -
  AB3423_RS08740 (AB3423_08740) comGA 1744514..1745488 (+) 975 WP_000697220.1 competence type IV pilus ATPase ComGA Machinery gene
  AB3423_RS08745 (AB3423_08745) comGB 1745460..1746530 (+) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  AB3423_RS08750 (AB3423_08750) comGC 1746544..1746855 (+) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  AB3423_RS08755 (AB3423_08755) comGD 1746833..1747279 (+) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  AB3423_RS08760 (AB3423_08760) comGE 1747266..1747565 (+) 300 WP_000844413.1 hypothetical protein Machinery gene
  AB3423_RS08765 (AB3423_08765) comGF 1747483..1747980 (+) 498 WP_001789864.1 competence type IV pilus minor pilin ComGF Machinery gene
  AB3423_RS08770 (AB3423_08770) - 1748077..1748223 (+) 147 WP_001789879.1 hypothetical protein -
  AB3423_RS08775 (AB3423_08775) - 1748213..1748737 (+) 525 WP_001015121.1 shikimate kinase -
  AB3423_RS08780 (AB3423_08780) gcvT 1748896..1749987 (+) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  AB3423_RS08785 (AB3423_08785) gcvPA 1750007..1751353 (+) 1347 WP_117200971.1 aminomethyl-transferring glycine dehydrogenase subunit GcvPA -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 41447.84 Da        Isoelectric Point: 10.0606

>NTDB_id=1026041 AB3423_RS08745 WP_000776422.1 1745460..1746530(+) (comGB) [Staphylococcus aureus strain TUM20913]
MKLQWINTFKLHSKKRQLSKAQQIDLLSNLCNLLKYGFTLYQSFQFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIG
YSDTIVMQVYLAERFGNIIDVLEETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNNLNMLNKINFVMKLPLISGYFQLFKTYFVTNELVLFYKNGITLQ
SIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQILEKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIK
QTQFLQPILFLILGLFIVAIYLVIMLPMFQMMQSIK

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=1026041 AB3423_RS08745 WP_000776422.1 1745460..1746530(+) (comGB) [Staphylococcus aureus strain TUM20913]
GTGAAACTACAATGGATAAATACATTTAAACTACATTCTAAGAAGCGACAATTAAGTAAGGCCCAACAAATCGATTTACT
TTCAAATTTATGTAATTTGTTGAAATATGGTTTCACTCTGTATCAAAGTTTTCAATTTTTAAATCTTCAAATGACATATA
AAAATAAGCAATTAGGTACCACCATTCTAAGTGAAATTTCAAATGGTGCACCATGCAATCAAATATTATCACTGATAGGT
TATAGCGATACTATCGTCATGCAAGTATATTTGGCAGAAAGATTTGGCAATATTATAGACGTTCTAGAAGAAACCGTAAA
TTATATGAAAGTGAATAGAAAGTCAGAACAACGATTGTTAAAGACACTGCAATACCCCTTAATACTAGTTTCTATCTTTA
TTGCTATGATTATTATATTAAACCTCACAGTAATTCCACAGTTTCAACAATTATATACTTCTATGAATATTCAACTATCT
TCTTTTCAAAAAACATTGTCTTTTTTCATTACCAGCTTACCTACTATAATTGTAGTAATGCTCATAATAGTATCTATGTT
GGCTATTATTATGAAATTAATTTATAACAATTTAAATATGCTCAATAAGATAAACTTTGTGATGAAACTACCGCTAATAT
CAGGCTATTTCCAATTATTTAAAACTTATTTTGTAACTAATGAATTAGTGTTGTTTTATAAAAATGGTATTACACTTCAA
TCAATAGTAGACGTTTATATTAACCATAGTAGTGATCCATTTAGACAGTTTCTAGGTAAATACTTATTAACTTATTCAGA
AATGGGATATGGTTTGCCTCAAATTTTAGAAAAACTAAAATGCTTTAAGCCTCAATTAATTAAGTTTGTGCTACAAGGTG
AAAAGAGAGGGAAGCTAGAAGTAGAACTAAAGTTATATTCACAAATATTAGTAAAACAAATAGAAGATAAAGCGATAAAA
CAGACTCAGTTTTTACAGCCTATTTTATTTTTGATTTTAGGTTTATTTATTGTCGCAATTTATTTAGTAATTATGTTACC
AATGTTTCAAATGATGCAAAGTATAAAATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(227-347)

Type II secretion system (T2SS), protein F (T2SSF)

(27-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB Staphylococcus aureus MW2

100

100

1
  comGB Staphylococcus aureus N315

100

100

1

Multiple sequence alignment