Detailed information NTG1026022

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3423_RS03015
• Genome accession: NZ_CP162461
• Coordinates: 648259..649146 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20913
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 643259..654146

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3423_RS02985 (AB3423_02985)	-	643991..644752 (+)	762	Protein_573	alpha/beta hydrolase	-
AB3423_RS02990 (AB3423_02990)	-	644997..645452 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3423_RS02995 (AB3423_02995)	-	645574..645675 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3423_RS03000 (AB3423_03000)	-	645735..647159 (-)	1425	WP_000953748.1	alkaline phosphatase	-
AB3423_RS03005 (AB3423_03005)	-	647357..647557 (+)	201	WP_000604727.1	hypothetical protein	-
AB3423_RS03010 (AB3423_03010)	braR	647583..648248 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3423_RS03015 (AB3423_03015)	braS	648259..649146 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3423_RS03020 (AB3423_03020)	-	649254..650009 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3423_RS03025 (AB3423_03025)	-	650006..652006 (+)	2001	WP_000776740.1	ABC transporter permease	-
AB3423_RS03030 (AB3423_03030)	-	652665..652778 (+)	114	Protein_582	hypothetical protein	-
AB3423_RS03035 (AB3423_03035)	-	653160..653420 (+)	261	WP_001791974.1	hypothetical protein	-
AB3423_RS03040 (AB3423_03040)	-	653430..653927 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3423_RS03045 (AB3423_03045)	-	654035..654127 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1026022 AB3423_RS03015 WP_000143417.1 648259..649146(+) (braS) [Staphylococcus aureus strain TUM20913]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026022 AB3423_RS03015 WP_000143417.1 648259..649146(+) (braS) [Staphylococcus aureus strain TUM20913]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99