Detailed information NTG1026012

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3437_RS11040
• Genome accession: NZ_CP162458
• Coordinates: 2230733..2231620 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20914
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2225733..2236620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3437_RS11010 (AB3437_10995)	-	2226465..2227226 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
AB3437_RS11015 (AB3437_11000)	-	2227471..2227926 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3437_RS11020 (AB3437_11005)	-	2228048..2228149 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3437_RS11025 (AB3437_11010)	-	2228209..2229633 (-)	1425	WP_000953744.1	alkaline phosphatase	-
AB3437_RS11030 (AB3437_11015)	-	2229831..2230031 (+)	201	WP_000604728.1	hypothetical protein	-
AB3437_RS11035 (AB3437_11020)	braR	2230057..2230722 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3437_RS11040 (AB3437_11025)	braS	2230733..2231620 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3437_RS11045 (AB3437_11030)	-	2231728..2232483 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3437_RS11050 (AB3437_11035)	-	2232480..2234480 (+)	2001	WP_000776751.1	ABC transporter permease	-
AB3437_RS11055 (AB3437_11040)	-	2235139..2235252 (+)	114	WP_011447078.1	hypothetical protein	-
AB3437_RS11060 (AB3437_11045)	-	2235634..2235894 (+)	261	WP_001789910.1	hypothetical protein	-
AB3437_RS11065 (AB3437_11050)	-	2235904..2236401 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3437_RS11070 (AB3437_11055)	-	2236509..2236601 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1026012 AB3437_RS11040 WP_000143419.1 2230733..2231620(+) (braS) [Staphylococcus aureus strain TUM20914]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1026012 AB3437_RS11040 WP_000143419.1 2230733..2231620(+) (braS) [Staphylococcus aureus strain TUM20914]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997