Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   AB3447_RS13445 Genome accession   NZ_CP162456
Coordinates   2721981..2722697 (-) Length   238 a.a.
NCBI ID   WP_031794497.1    Uniprot ID   -
Organism   Staphylococcus aureus strain TUM20915     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2716981..2727697
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB3447_RS13425 (AB3447_13425) - 2718073..2719023 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  AB3447_RS13430 (AB3447_13430) - 2719172..2720656 (+) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  AB3447_RS13435 (AB3447_13435) - 2720653..2721612 (+) 960 WP_117201054.1 carbohydrate kinase -
  AB3447_RS13440 (AB3447_13440) - 2721800..2721909 (-) 110 Protein_2605 hypothetical protein -
  AB3447_RS13445 (AB3447_13445) agrA 2721981..2722697 (-) 717 WP_031794497.1 quorum-sensing response regulator AgrA Regulator
  AB3447_RS13450 (AB3447_13450) agrC 2722716..2724008 (-) 1293 WP_172576662.1 quorum-sensing sensor histidine kinase AgrC -
  AB3447_RS13455 (AB3447_13455) agrD 2724033..2724173 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  AB3447_RS13460 (AB3447_13460) - 2724177..2724740 (-) 564 WP_001105705.1 accessory gene regulator AgrB -
  AB3447_RS13465 (AB3447_13465) - 2724976..2725110 (+) 135 WP_001823225.1 delta-lysin family phenol-soluble modulin -
  AB3447_RS13470 (AB3447_13470) - 2725709..2726494 (-) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  AB3447_RS13475 (AB3447_13475) - 2726855..2727481 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27975.01 Da        Isoelectric Point: 6.3009

>NTDB_id=1025968 AB3447_RS13445 WP_031794497.1 2721981..2722697(-) (agrA) [Staphylococcus aureus strain TUM20915]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNRFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1025968 AB3447_RS13445 WP_031794497.1 2721981..2722697(-) (agrA) [Staphylococcus aureus strain TUM20915]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGATTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment