Detailed information NTG1025964

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3447_RS10380
• Genome accession: NZ_CP162456
• Coordinates: 2113158..2114045 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20915
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2108158..2119045

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3447_RS10350 (AB3447_10350)	-	2108893..2109652 (+)	760	Protein_2001	alpha/beta hydrolase	-
AB3447_RS10355 (AB3447_10355)	-	2109897..2110352 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3447_RS10360 (AB3447_10360)	-	2110474..2110575 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3447_RS10365 (AB3447_10365)	-	2110634..2112058 (-)	1425	WP_000953748.1	alkaline phosphatase	-
AB3447_RS10370 (AB3447_10370)	-	2112256..2112456 (+)	201	WP_000604727.1	hypothetical protein	-
AB3447_RS10375 (AB3447_10375)	braR	2112482..2113147 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3447_RS10380 (AB3447_10380)	braS	2113158..2114045 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3447_RS10385 (AB3447_10385)	-	2114153..2114908 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3447_RS10390 (AB3447_10390)	-	2114905..2116905 (+)	2001	WP_000776740.1	ABC transporter permease	-
AB3447_RS10395 (AB3447_10395)	-	2117564..2117677 (+)	114	Protein_2010	hypothetical protein	-
AB3447_RS10400 (AB3447_10400)	-	2118059..2118319 (+)	261	WP_001791974.1	hypothetical protein	-
AB3447_RS10405 (AB3447_10405)	-	2118329..2118826 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3447_RS10410 (AB3447_10410)	-	2118934..2119026 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1025964 AB3447_RS10380 WP_000143417.1 2113158..2114045(+) (braS) [Staphylococcus aureus strain TUM20915]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025964 AB3447_RS10380 WP_000143417.1 2113158..2114045(+) (braS) [Staphylococcus aureus strain TUM20915]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99