Detailed information NTG1025927

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3434_RS11615
• Genome accession: NZ_CP162454
• Coordinates: 2358898..2359785 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM20926
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2353898..2364785

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3434_RS11585 (AB3434_11585)	-	2354630..2355391 (+)	762	Protein_2235	alpha/beta hydrolase	-
AB3434_RS11590 (AB3434_11590)	-	2355636..2356091 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3434_RS11595 (AB3434_11595)	-	2356213..2356314 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3434_RS11600 (AB3434_11600)	-	2356374..2357798 (-)	1425	WP_000953748.1	alkaline phosphatase	-
AB3434_RS11605 (AB3434_11605)	-	2357996..2358196 (+)	201	WP_000604727.1	hypothetical protein	-
AB3434_RS11610 (AB3434_11610)	braR	2358222..2358887 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3434_RS11615 (AB3434_11615)	braS	2358898..2359785 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3434_RS11620 (AB3434_11620)	-	2359893..2360648 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3434_RS11625 (AB3434_11625)	-	2360645..2362645 (+)	2001	WP_000776740.1	ABC transporter permease	-
AB3434_RS11630 (AB3434_11630)	-	2363304..2363417 (+)	114	Protein_2244	hypothetical protein	-
AB3434_RS11635 (AB3434_11635)	-	2363799..2364059 (+)	261	WP_001791974.1	hypothetical protein	-
AB3434_RS11640 (AB3434_11640)	-	2364069..2364566 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3434_RS11645 (AB3434_11645)	-	2364674..2364766 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1025927 AB3434_RS11615 WP_000143417.1 2358898..2359785(+) (braS) [Staphylococcus aureus strain TUM20926]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025927 AB3434_RS11615 WP_000143417.1 2358898..2359785(+) (braS) [Staphylococcus aureus strain TUM20926]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99