Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   AS97_RS03800 Genome accession   NZ_CP007153
Coordinates   841694..842353 (+) Length   219 a.a.
NCBI ID   WP_086708263.1    Uniprot ID   A0ABN1EKF9
Organism   Streptomyces sp. AgN23     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 836694..847353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AS97_RS46835 - 836765..837119 (+) 355 Protein_772 alpha/beta hydrolase fold domain-containing protein -
  AS97_RS03780 (AS97_41905) - 837344..838498 (-) 1155 WP_086708257.1 Gfo/Idh/MocA family oxidoreductase -
  AS97_RS03785 (AS97_21790) - 838611..839627 (+) 1017 WP_210564335.1 LacI family DNA-binding transcriptional regulator -
  AS97_RS03790 (AS97_21800) - 840096..840338 (-) 243 WP_059142641.1 hypothetical protein -
  AS97_RS03795 (AS97_41910) - 840497..841678 (+) 1182 WP_059142640.1 sensor histidine kinase -
  AS97_RS03800 (AS97_41915) vraR 841694..842353 (+) 660 WP_086708263.1 response regulator transcription factor Regulator
  AS97_RS03805 (AS97_21820) - 842547..843191 (+) 645 WP_059142681.1 TetR/AcrR family transcriptional regulator -
  AS97_RS03810 (AS97_21825) - 843277..844506 (+) 1230 WP_210564336.1 cytochrome P450 -
  AS97_RS03815 (AS97_21830) - 844521..844715 (+) 195 WP_086708265.1 ferredoxin -
  AS97_RS03820 (AS97_21835) - 844834..845598 (+) 765 WP_210564337.1 SDR family NAD(P)-dependent oxidoreductase -
  AS97_RS03825 (AS97_41920) - 845623..846228 (-) 606 WP_059142680.1 GPP34 family phosphoprotein -
  AS97_RS48440 - 846628..846753 (+) 126 WP_260613207.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 22999.48 Da        Isoelectric Point: 6.2355

>NTDB_id=102589 AS97_RS03800 WP_086708263.1 841694..842353(+) (vraR) [Streptomyces sp. AgN23]
MIHVLLVDDDAIVRAGLRLMLGGAPDIEVVAEAADGAEVPALVAAQRPDVVLMDIRMPGVDGLTATTELRARPGAPEVLV
LTTFHTDAHVLRALRGGAAGFLLKDTPPQDIVTAIRTVAAGDPVLSPAVTRRLIEQVAGGGQEDRATAARARLALLGERE
REVARAVGGGRSNAEIARELHLALPTVKAHVSRILTRLDLNNRVQIALLVHDAGESYGG

Nucleotide


Download         Length: 660 bp        

>NTDB_id=102589 AS97_RS03800 WP_086708263.1 841694..842353(+) (vraR) [Streptomyces sp. AgN23]
GTGATCCATGTCCTGCTGGTGGACGACGACGCGATCGTACGGGCCGGGCTGCGCCTGATGCTGGGCGGTGCCCCGGACAT
CGAGGTCGTCGCGGAGGCCGCCGACGGGGCGGAGGTGCCGGCCCTGGTCGCCGCGCAGCGGCCCGATGTGGTGCTGATGG
ACATCCGGATGCCGGGTGTGGACGGGCTGACCGCCACCACCGAGCTCCGGGCCCGGCCCGGCGCCCCGGAGGTGCTGGTG
CTGACCACTTTCCACACCGACGCGCATGTGCTGCGGGCGCTGCGCGGCGGGGCGGCCGGGTTCCTCCTCAAGGACACCCC
GCCACAGGACATCGTCACGGCCATCCGGACGGTGGCCGCCGGGGATCCGGTGCTCTCCCCCGCCGTCACCCGCCGCCTCA
TCGAGCAGGTGGCGGGCGGCGGGCAGGAGGACCGGGCCACCGCCGCCCGGGCCCGGCTGGCGCTGCTGGGCGAGCGGGAG
CGGGAGGTGGCCCGGGCGGTCGGGGGCGGCCGCTCCAACGCGGAGATCGCCCGGGAGCTGCATCTGGCGTTGCCGACGGT
GAAGGCCCATGTGTCGCGCATCCTGACCCGGCTGGACCTCAACAACCGCGTCCAGATCGCCCTGTTGGTCCACGACGCCG
GCGAGTCGTACGGCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(156-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.537

93.607

0.361

Multiple sequence alignment