Detailed information NTG1025880

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3442_RS10875
• Genome accession: NZ_CP162453
• Coordinates: 2210141..2211028 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM20929
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2205141..2216028

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3442_RS10845 (AB3442_10845)	-	2205873..2206634 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
AB3442_RS10850 (AB3442_10850)	-	2206879..2207334 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3442_RS10855 (AB3442_10855)	-	2207456..2207557 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3442_RS10860 (AB3442_10860)	-	2207617..2209041 (-)	1425	WP_000953744.1	alkaline phosphatase	-
AB3442_RS10865 (AB3442_10865)	-	2209239..2209439 (+)	201	WP_000604732.1	hypothetical protein	-
AB3442_RS10870 (AB3442_10870)	braR	2209465..2210130 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3442_RS10875 (AB3442_10875)	braS	2210141..2211028 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3442_RS10880 (AB3442_10880)	-	2211136..2211891 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3442_RS10885 (AB3442_10885)	-	2211888..2213888 (+)	2001	WP_000776751.1	ABC transporter permease	-
AB3442_RS10890 (AB3442_10890)	-	2214547..2214660 (+)	114	WP_011447078.1	hypothetical protein	-
AB3442_RS10895 (AB3442_10895)	-	2215042..2215302 (+)	261	WP_001789910.1	hypothetical protein	-
AB3442_RS10900 (AB3442_10900)	-	2215312..2215809 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3442_RS10905 (AB3442_10905)	-	2215917..2216009 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025880 AB3442_RS10875 WP_000143419.1 2210141..2211028(+) (braS) [Staphylococcus aureus strain TUM20929]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025880 AB3442_RS10875 WP_000143419.1 2210141..2211028(+) (braS) [Staphylococcus aureus strain TUM20929]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997