Detailed information NTG1025793

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3455_RS13495
• Genome accession: NZ_CP162447
• Coordinates: 2706294..2707337 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22173
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2701294..2712337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3455_RS13465 (AB3455_13465)	-	2701712..2702968 (-)	1257	WP_001795438.1	aminopeptidase	-
AB3455_RS13470 (AB3455_13470)	-	2702971..2703171 (-)	201	WP_000180461.1	DUF1128 family protein	-
AB3455_RS13475 (AB3455_13475)	-	2703318..2703782 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3455_RS13480 (AB3455_13480)	-	2703789..2704064 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3455_RS13485 (AB3455_13485)	-	2704342..2705559 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AB3455_RS13490 (AB3455_13490)	vraR	2705675..2706304 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AB3455_RS13495 (AB3455_13495)	vraS	2706294..2707337 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3455_RS13500 (AB3455_13500)	liaF	2707334..2708035 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3455_RS13505 (AB3455_13505)	-	2708050..2708436 (-)	387	WP_001110179.1	hypothetical protein	-
AB3455_RS13510 (AB3455_13510)	map	2708653..2709411 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3455_RS13515 (AB3455_13515)	-	2709939..2710925 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3455_RS13520 (AB3455_13520)	-	2711356..2711769 (-)	414	WP_001549145.1	hypothetical protein	-
AB3455_RS13525 (AB3455_13525)	-	2711798..2711908 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1025793 AB3455_RS13495 WP_001017131.1 2706294..2707337(-) (vraS) [Staphylococcus aureus strain TUM22173]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025793 AB3455_RS13495 WP_001017131.1 2706294..2707337(-) (vraS) [Staphylococcus aureus strain TUM22173]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1