Detailed information NTG1025756

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3455_RS03030
• Genome accession: NZ_CP162447
• Coordinates: 592684..593571 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22173
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 587684..598571

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3455_RS03000 (AB3455_03000)	-	587703..587795 (+)	93	WP_010956583.1	hypothetical protein	-
AB3455_RS03005 (AB3455_03005)	-	587903..588400 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3455_RS03010 (AB3455_03010)	-	588410..588670 (-)	261	WP_001789910.1	hypothetical protein	-
AB3455_RS03015 (AB3455_03015)	-	589052..589165 (-)	114	WP_001791776.1	hypothetical protein	-
AB3455_RS03020 (AB3455_03020)	-	589824..591824 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3455_RS03025 (AB3455_03025)	-	591821..592576 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3455_RS03030 (AB3455_03030)	braS	592684..593571 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3455_RS03035 (AB3455_03035)	braR	593582..594247 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3455_RS03040 (AB3455_03040)	-	594273..594473 (-)	201	WP_000604728.1	hypothetical protein	-
AB3455_RS03045 (AB3455_03045)	-	594671..596095 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AB3455_RS03050 (AB3455_03050)	-	596155..596256 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3455_RS03055 (AB3455_03055)	-	596378..596833 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3455_RS03060 (AB3455_03060)	-	597078..597839 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025756 AB3455_RS03030 WP_000143419.1 592684..593571(-) (braS) [Staphylococcus aureus strain TUM22173]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025756 AB3455_RS03030 WP_000143419.1 592684..593571(-) (braS) [Staphylococcus aureus strain TUM22173]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997