Detailed information NTG1025718

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3451_RS04375
• Genome accession: NZ_CP162445
• Coordinates: 816888..817775 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22178
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 811888..822775

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3451_RS04345 (AB3451_04345)	-	811907..811999 (+)	93	WP_010956583.1	hypothetical protein	-
AB3451_RS04350 (AB3451_04350)	-	812107..812604 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3451_RS04355 (AB3451_04355)	-	812614..812874 (-)	261	WP_001791974.1	hypothetical protein	-
AB3451_RS04360 (AB3451_04360)	-	813256..813369 (-)	114	Protein_818	hypothetical protein	-
AB3451_RS04365 (AB3451_04365)	-	814028..816028 (-)	2001	WP_368409512.1	ABC transporter permease	-
AB3451_RS04370 (AB3451_04370)	-	816025..816780 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3451_RS04375 (AB3451_04375)	braS	816888..817775 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3451_RS04380 (AB3451_04380)	braR	817786..818451 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3451_RS04385 (AB3451_04385)	-	818477..818677 (-)	201	WP_000604727.1	hypothetical protein	-
AB3451_RS04390 (AB3451_04390)	-	818875..820299 (+)	1425	WP_000953748.1	alkaline phosphatase	-
AB3451_RS04395 (AB3451_04395)	-	820359..820460 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3451_RS04400 (AB3451_04400)	-	820582..821037 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3451_RS04405 (AB3451_04405)	-	821282..822043 (-)	762	Protein_827	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1025718 AB3451_RS04375 WP_000143417.1 816888..817775(-) (braS) [Staphylococcus aureus strain TUM22178]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025718 AB3451_RS04375 WP_000143417.1 816888..817775(-) (braS) [Staphylococcus aureus strain TUM22178]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99