Detailed information NTG1025712

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3451_RS00600
• Genome accession: NZ_CP162445
• Coordinates: 88562..89605 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22178
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 83562..94605

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3451_RS00570 (AB3451_00570)	-	83990..85246 (-)	1257	WP_001793428.1	aminopeptidase	-
AB3451_RS00575 (AB3451_00575)	-	85249..85449 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB3451_RS00580 (AB3451_00580)	-	85596..86060 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3451_RS00585 (AB3451_00585)	-	86067..86342 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3451_RS00590 (AB3451_00590)	-	86620..87831 (+)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
AB3451_RS00595 (AB3451_00595)	vraR	87943..88572 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB3451_RS00600 (AB3451_00600)	vraS	88562..89605 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3451_RS00605 (AB3451_00605)	liaF	89602..90303 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3451_RS00610 (AB3451_00610)	-	90318..90704 (-)	387	WP_001110179.1	hypothetical protein	-
AB3451_RS00615 (AB3451_00615)	map	90921..91679 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3451_RS00620 (AB3451_00620)	-	92210..93196 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3451_RS00625 (AB3451_00625)	-	93686..94099 (-)	414	WP_001837236.1	hypothetical protein	-
AB3451_RS00630 (AB3451_00630)	-	94128..94239 (-)	112	Protein_86	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1025712 AB3451_RS00600 WP_001017131.1 88562..89605(-) (vraS) [Staphylococcus aureus strain TUM22178]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025712 AB3451_RS00600 WP_001017131.1 88562..89605(-) (vraS) [Staphylococcus aureus strain TUM22178]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1