Detailed information NTG1025672

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3441_RS02955
• Genome accession: NZ_CP162444
• Coordinates: 622299..623186 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22182
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 617299..628186

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3441_RS02925 (AB3441_02925)	-	618031..618792 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
AB3441_RS02930 (AB3441_02930)	-	619037..619492 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3441_RS02935 (AB3441_02935)	-	619614..619715 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3441_RS02940 (AB3441_02940)	-	619775..621199 (-)	1425	WP_000953744.1	alkaline phosphatase	-
AB3441_RS02945 (AB3441_02945)	-	621397..621597 (+)	201	WP_000604728.1	hypothetical protein	-
AB3441_RS02950 (AB3441_02950)	braR	621623..622288 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3441_RS02955 (AB3441_02955)	braS	622299..623186 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3441_RS02960 (AB3441_02960)	-	623294..624049 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3441_RS02965 (AB3441_02965)	-	624046..626046 (+)	2001	WP_000776751.1	ABC transporter permease	-
AB3441_RS02970 (AB3441_02970)	-	626705..626818 (+)	114	WP_011447078.1	hypothetical protein	-
AB3441_RS02975 (AB3441_02975)	-	627200..627460 (+)	261	WP_001789910.1	hypothetical protein	-
AB3441_RS02980 (AB3441_02980)	-	627470..627967 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3441_RS02985 (AB3441_02985)	-	628075..628167 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025672 AB3441_RS02955 WP_000143419.1 622299..623186(+) (braS) [Staphylococcus aureus strain TUM22182]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025672 AB3441_RS02955 WP_000143419.1 622299..623186(+) (braS) [Staphylococcus aureus strain TUM22182]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997