Detailed information NTG1025634

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3438_RS06790
• Genome accession: NZ_CP162442
• Coordinates: 1376624..1377667 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22188
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1371624..1382667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3438_RS06760 (AB3438_06760)	-	1371990..1372101 (+)	112	Protein_1314	hypothetical protein	-
AB3438_RS06765 (AB3438_06765)	-	1372130..1372543 (+)	414	WP_001837236.1	hypothetical protein	-
AB3438_RS06770 (AB3438_06770)	-	1373033..1374019 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3438_RS06775 (AB3438_06775)	map	1374550..1375308 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3438_RS06780 (AB3438_06780)	-	1375525..1375911 (+)	387	WP_001110179.1	hypothetical protein	-
AB3438_RS06785 (AB3438_06785)	liaF	1375926..1376627 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3438_RS06790 (AB3438_06790)	vraS	1376624..1377667 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3438_RS06795 (AB3438_06795)	vraR	1377657..1378286 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB3438_RS06800 (AB3438_06800)	-	1378398..1379609 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
AB3438_RS06805 (AB3438_06805)	-	1379887..1380162 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3438_RS06810 (AB3438_06810)	-	1380169..1380633 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3438_RS06815 (AB3438_06815)	-	1380780..1380980 (+)	201	WP_000180460.1	DUF1128 family protein	-
AB3438_RS06820 (AB3438_06820)	-	1380983..1382239 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1025634 AB3438_RS06790 WP_001017131.1 1376624..1377667(+) (vraS) [Staphylococcus aureus strain TUM22188]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025634 AB3438_RS06790 WP_001017131.1 1376624..1377667(+) (vraS) [Staphylococcus aureus strain TUM22188]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1