Detailed information NTG1025534

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3435_RS02745
• Genome accession: NZ_CP162438
• Coordinates: 513776..514663 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TUM22458
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 508776..519663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3435_RS02715 (AB3435_02715)	-	508795..508887 (+)	93	WP_010956583.1	hypothetical protein	-
AB3435_RS02720 (AB3435_02720)	-	508995..509492 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3435_RS02725 (AB3435_02725)	-	509502..509762 (-)	261	WP_001791974.1	hypothetical protein	-
AB3435_RS02730 (AB3435_02730)	-	510144..510257 (-)	114	Protein_542	hypothetical protein	-
AB3435_RS02735 (AB3435_02735)	-	510916..512916 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3435_RS02740 (AB3435_02740)	-	512913..513668 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3435_RS02745 (AB3435_02745)	braS	513776..514663 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3435_RS02750 (AB3435_02750)	braR	514674..515339 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3435_RS02755 (AB3435_02755)	-	515365..515565 (-)	201	WP_000604730.1	hypothetical protein	-
AB3435_RS02760 (AB3435_02760)	-	515763..517187 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB3435_RS02765 (AB3435_02765)	-	517247..517348 (-)	102	WP_000731976.1	SE2200 family small protein	-
AB3435_RS02770 (AB3435_02770)	-	517470..517925 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3435_RS02775 (AB3435_02775)	-	518170..518931 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025534 AB3435_RS02745 WP_000143425.1 513776..514663(-) (braS) [Staphylococcus aureus strain TUM22458]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025534 AB3435_RS02745 WP_000143425.1 513776..514663(-) (braS) [Staphylococcus aureus strain TUM22458]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1