Detailed information NTG1025493

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3443_RS00625
• Genome accession: NZ_CP162437
• Coordinates: 123673..124716 (+)
• Length: 347 a.a.
• NCBI ID: WP_117219619.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain TUM22698
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 118673..129716

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3443_RS00595 (AB3443_00595)	-	119043..119153 (+)	111	WP_001790257.1	hypothetical protein	-
AB3443_RS00600 (AB3443_00600)	-	119182..119595 (+)	414	WP_001549145.1	hypothetical protein	-
AB3443_RS00605 (AB3443_00605)	-	120026..121012 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3443_RS00610 (AB3443_00610)	map	121599..122357 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3443_RS00615 (AB3443_00615)	-	122574..122960 (+)	387	WP_001110179.1	hypothetical protein	-
AB3443_RS00620 (AB3443_00620)	liaF	122975..123676 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3443_RS00625 (AB3443_00625)	vraS	123673..124716 (+)	1044	WP_117219619.1	sensor histidine kinase	Regulator
AB3443_RS00630 (AB3443_00630)	vraR	124706..125335 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
AB3443_RS00635 (AB3443_00635)	-	125451..126668 (-)	1218	WP_000037069.1	YihY/virulence factor BrkB family protein	-
AB3443_RS00640 (AB3443_00640)	-	126946..127221 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3443_RS00645 (AB3443_00645)	-	127228..127692 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3443_RS00650 (AB3443_00650)	-	127839..128039 (+)	201	WP_000180461.1	DUF1128 family protein	-
AB3443_RS00655 (AB3443_00655)	-	128042..129298 (+)	1257	WP_001795438.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40043.58 Da
• Isoelectric Point: 6.4212

>NTDB_id=1025493 AB3443_RS00625 WP_117219619.1 123673..124716(+) (vraS) [Staphylococcus aureus strain TUM22698]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMKGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025493 AB3443_RS00625 WP_117219619.1 123673..124716(+) (vraS) [Staphylococcus aureus strain TUM22698]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGAAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997