Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | AB3430_RS05015 | Genome accession | NZ_CP162430 |
| Coordinates | 968151..969779 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain TUM22702 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 899769..971150 | 968151..969779 | within | 0 |
Gene organization within MGE regions
Location: 899769..971150
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AB3430_RS04660 (AB3430_04660) | - | 899771..901378 (+) | 1608 | Protein_912 | heavy metal translocating P-type ATPase | - |
| AB3430_RS04665 (AB3430_04665) | - | 902604..903860 (+) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| AB3430_RS04670 (AB3430_04670) | - | 904275..904514 (+) | 240 | WP_001282728.1 | hypothetical protein | - |
| AB3430_RS04675 (AB3430_04675) | - | 904546..905220 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| AB3430_RS04680 (AB3430_04680) | - | 905277..905600 (-) | 324 | Protein_916 | heavy metal translocating P-type ATPase | - |
| AB3430_RS04685 (AB3430_04685) | - | 905930..906256 (-) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| AB3430_RS04690 (AB3430_04690) | - | 906463..906822 (+) | 360 | WP_001631039.1 | hypothetical protein | - |
| AB3430_RS04695 (AB3430_04695) | - | 906934..907272 (-) | 339 | Protein_919 | recombinase family protein | - |
| AB3430_RS04700 (AB3430_04700) | - | 907281..907910 (+) | 630 | Protein_920 | hypothetical protein | - |
| AB3430_RS04705 (AB3430_04705) | ccrA | 908097..909458 (+) | 1362 | WP_001631036.1 | cassette chromosome recombinase CcrA | Machinery gene |
| AB3430_RS04710 (AB3430_04710) | ccrB | 909455..911083 (+) | 1629 | WP_001631035.1 | cassette chromosome recombinase CcrB | Machinery gene |
| AB3430_RS04715 (AB3430_04715) | - | 911584..911934 (+) | 351 | WP_001631034.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| AB3430_RS04720 (AB3430_04720) | - | 912021..912101 (+) | 81 | Protein_924 | DUF960 family protein | - |
| AB3430_RS04725 (AB3430_04725) | - | 912187..913002 (-) | 816 | WP_000164963.1 | AAA family ATPase | - |
| AB3430_RS04730 (AB3430_04730) | - | 912995..914437 (-) | 1443 | WP_002451367.1 | Mu transposase C-terminal domain-containing protein | - |
| AB3430_RS04735 (AB3430_04735) | - | 914409..915002 (-) | 594 | WP_000690638.1 | recombinase family protein | - |
| AB3430_RS04740 (AB3430_04740) | blaI | 915266..915646 (-) | 381 | WP_000182645.1 | penicillinase repressor BlaI | - |
| AB3430_RS04745 (AB3430_04745) | blaR1 | 915636..917393 (-) | 1758 | WP_001096381.1 | beta-lactam sensor/signal transducer BlaR1 | - |
| AB3430_RS04750 (AB3430_04750) | blaZ | 917500..918346 (+) | 847 | Protein_930 | penicillin-hydrolyzing class A beta-lactamase BlaZ | - |
| AB3430_RS04755 (AB3430_04755) | - | 918647..918886 (+) | 240 | Protein_931 | DUF960 family protein | - |
| AB3430_RS04760 (AB3430_04760) | - | 918902..919405 (+) | 504 | WP_001631032.1 | DUF1643 domain-containing protein | - |
| AB3430_RS04765 (AB3430_04765) | - | 919420..919640 (+) | 221 | Protein_933 | hypothetical protein | - |
| AB3430_RS04770 (AB3430_04770) | - | 919803..920213 (+) | 411 | WP_001631031.1 | DUF2871 domain-containing protein | - |
| AB3430_RS04775 (AB3430_04775) | - | 920885..921382 (+) | 498 | WP_001631030.1 | GNAT family N-acetyltransferase | - |
| AB3430_RS04780 (AB3430_04780) | - | 921444..921660 (+) | 217 | Protein_936 | IS5/IS1182 family transposase | - |
| AB3430_RS04785 (AB3430_04785) | - | 921705..922907 (-) | 1203 | WP_001631029.1 | restriction endonuclease subunit S | - |
| AB3430_RS04790 (AB3430_04790) | - | 922900..923043 (-) | 144 | WP_001631028.1 | restriction endonuclease subunit R | - |
| AB3430_RS04795 (AB3430_04795) | rlmH | 923144..923623 (-) | 480 | WP_000704775.1 | 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH | - |
| AB3430_RS04800 (AB3430_04800) | adsA | 923991..926309 (-) | 2319 | WP_341262117.1 | LPXTG-anchored adenosine synthase AdsA | - |
| AB3430_RS04805 (AB3430_04805) | - | 926536..927336 (-) | 801 | WP_000088649.1 | MBL fold metallo-hydrolase | - |
| AB3430_RS04810 (AB3430_04810) | - | 927725..928513 (-) | 789 | WP_001104165.1 | two-component system regulatory protein YycI | - |
| AB3430_RS04815 (AB3430_04815) | yycH | 928514..929848 (-) | 1335 | WP_001060140.1 | two-component system activity regulator YycH | - |
| AB3430_RS04820 (AB3430_04820) | walK | 929841..931667 (-) | 1827 | WP_000871607.1 | cell wall metabolism sensor histidine kinase WalK | - |
| AB3430_RS04825 (AB3430_04825) | yycF | 931680..932381 (-) | 702 | WP_000101976.1 | response regulator YycF | - |
| AB3430_RS04840 (AB3430_04840) | - | 933584..934867 (-) | 1284 | WP_000095328.1 | adenylosuccinate synthase | - |
| AB3430_RS04845 (AB3430_04845) | dnaB | 935145..936545 (-) | 1401 | WP_000375647.1 | replicative DNA helicase | - |
| AB3430_RS04850 (AB3430_04850) | rplI | 936577..937023 (-) | 447 | WP_000864305.1 | 50S ribosomal protein L9 | - |
| AB3430_RS04855 (AB3430_04855) | gdpP | 937020..938987 (-) | 1968 | WP_001081640.1 | cyclic-di-AMP phosphodiesterase GdpP | - |
| AB3430_RS04860 (AB3430_04860) | - | 939002..939940 (-) | 939 | WP_341262116.1 | YybS family protein | - |
| AB3430_RS04865 (AB3430_04865) | - | 940233..941201 (-) | 969 | WP_000186490.1 | alpha/beta fold hydrolase family protein | - |
| AB3430_RS04870 (AB3430_04870) | - | 941564..941893 (-) | 330 | WP_000628051.1 | AzlD domain-containing protein | - |
| AB3430_RS04875 (AB3430_04875) | - | 941890..942585 (-) | 696 | WP_000190726.1 | AzlC family ABC transporter permease | - |
| AB3430_RS04880 (AB3430_04880) | serS | 943236..944522 (-) | 1287 | WP_000884332.1 | serine--tRNA ligase | - |
| AB3430_RS04885 (AB3430_04885) | hutH | 944901..946415 (-) | 1515 | WP_000177465.1 | histidine ammonia-lyase | - |
| AB3430_RS04890 (AB3430_04890) | - | 946535..947209 (-) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| AB3430_RS04895 (AB3430_04895) | - | 947293..947634 (+) | 342 | WP_001797647.1 | hydroxymethylglutaryl-CoA synthase | - |
| AB3430_RS04900 (AB3430_04900) | - | 948471..949214 (+) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| AB3430_RS04905 (AB3430_04905) | - | 949311..949739 (+) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| AB3430_RS04910 (AB3430_04910) | mecA | 949785..951794 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| AB3430_RS04915 (AB3430_04915) | mecR1 | 951891..953648 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| AB3430_RS04920 (AB3430_04920) | mecI | 953648..954019 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| AB3430_RS04925 (AB3430_04925) | psm-mec | 954104..954172 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| AB3430_RS04930 (AB3430_04930) | - | 954506..955636 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| AB3430_RS04935 (AB3430_04935) | cstB | 955750..957084 (-) | 1335 | Protein_965 | persulfide dioxygenase-sulfurtransferase CstB | - |
| AB3430_RS04940 (AB3430_04940) | - | 957117..958181 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| AB3430_RS04945 (AB3430_04945) | cstR | 958317..958577 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| AB3430_RS04950 (AB3430_04950) | - | 958577..959215 (+) | 639 | Protein_968 | sulfite exporter TauE/SafE family protein | - |
| AB3430_RS04955 (AB3430_04955) | - | 959266..959328 (-) | 63 | Protein_969 | DNA repair protein RadC | - |
| AB3430_RS04960 (AB3430_04960) | - | 959560..960222 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| AB3430_RS04965 (AB3430_04965) | - | 960614..960673 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| AB3430_RS04970 (AB3430_04970) | erm(A) | 960756..961487 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| AB3430_RS04975 (AB3430_04975) | - | 961613..962395 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| AB3430_RS04980 (AB3430_04980) | - | 962546..962923 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| AB3430_RS04985 (AB3430_04985) | - | 962930..964822 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| AB3430_RS04990 (AB3430_04990) | - | 964819..965904 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| AB3430_RS04995 (AB3430_04995) | - | 966023..966340 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| AB3430_RS05000 (AB3430_05000) | - | 966361..966867 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| AB3430_RS05005 (AB3430_05005) | - | 966885..967196 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| AB3430_RS05010 (AB3430_05010) | - | 967283..967633 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| AB3430_RS05015 (AB3430_05015) | ccrB | 968151..969779 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| AB3430_RS05020 (AB3430_05020) | ccrA | 969801..971150 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=1025367 AB3430_RS05015 WP_001186602.1 968151..969779(-) (ccrB) [Staphylococcus aureus strain TUM22702]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=1025367 AB3430_RS05015 WP_001186602.1 968151..969779(-) (ccrB) [Staphylococcus aureus strain TUM22702]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGCCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGCCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |