Detailed information NTG1025361

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3430_RS04145
• Genome accession: NZ_CP162430
• Coordinates: 781016..781903 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TUM22702
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 776016..786903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3430_RS04115 (AB3430_04115)	-	776035..776127 (+)	93	WP_010956583.1	hypothetical protein	-
AB3430_RS04120 (AB3430_04120)	-	776235..776732 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3430_RS04125 (AB3430_04125)	-	776742..777002 (-)	261	WP_001791974.1	hypothetical protein	-
AB3430_RS04130 (AB3430_04130)	-	777384..777497 (-)	114	Protein_806	hypothetical protein	-
AB3430_RS04135 (AB3430_04135)	-	778156..780156 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3430_RS04140 (AB3430_04140)	-	780153..780908 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3430_RS04145 (AB3430_04145)	braS	781016..781903 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3430_RS04150 (AB3430_04150)	braR	781914..782579 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3430_RS04155 (AB3430_04155)	-	782605..782805 (-)	201	WP_000604730.1	hypothetical protein	-
AB3430_RS04160 (AB3430_04160)	-	783003..784427 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB3430_RS04165 (AB3430_04165)	-	784487..784588 (-)	102	WP_000731976.1	SE2200 family small protein	-
AB3430_RS04170 (AB3430_04170)	-	784710..785165 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3430_RS04175 (AB3430_04175)	-	785410..786171 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025361 AB3430_RS04145 WP_000143425.1 781016..781903(-) (braS) [Staphylococcus aureus strain TUM22702]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025361 AB3430_RS04145 WP_000143425.1 781016..781903(-) (braS) [Staphylococcus aureus strain TUM22702]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1