Detailed information NTG1025355

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3430_RS00155
• Genome accession: NZ_CP162430
• Coordinates: 28613..29656 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain TUM22702
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 23613..34656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3430_RS00125 (AB3430_00125)	-	24034..25290 (-)	1257	WP_001795108.1	aminopeptidase	-
AB3430_RS00130 (AB3430_00130)	-	25293..25493 (-)	201	WP_000180460.1	DUF1128 family protein	-
AB3430_RS00135 (AB3430_00135)	-	25640..26104 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3430_RS00140 (AB3430_00140)	-	26111..26386 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3430_RS00145 (AB3430_00145)	-	26664..27881 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
AB3430_RS00150 (AB3430_00150)	vraR	27994..28623 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB3430_RS00155 (AB3430_00155)	vraS	28613..29656 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
AB3430_RS00160 (AB3430_00160)	liaF	29653..30354 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3430_RS00165 (AB3430_00165)	-	30369..30755 (-)	387	WP_001110179.1	hypothetical protein	-
AB3430_RS00170 (AB3430_00170)	map	30972..31730 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3430_RS00175 (AB3430_00175)	-	32261..33247 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
AB3430_RS00180 (AB3430_00180)	-	33678..34091 (-)	414	WP_001557448.1	hypothetical protein	-
AB3430_RS00185 (AB3430_00185)	-	34120..34230 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1025355 AB3430_RS00155 WP_001017131.1 28613..29656(-) (vraS) [Staphylococcus aureus strain TUM22702]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025355 AB3430_RS00155 WP_001017131.1 28613..29656(-) (vraS) [Staphylococcus aureus strain TUM22702]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1