Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | AB3428_RS11480 | Genome accession | NZ_CP162428 |
| Coordinates | 2300245..2301873 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus strain TUM22707 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 2295024..2338748 | 2300245..2301873 | within | 0 |
| SCCmec | 2281904..2303244 | 2300245..2301873 | within | 0 |
Gene organization within MGE regions
Location: 2281904..2338748
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| AB3428_RS11375 (AB3428_11375) | mecA | 2281904..2283913 (-) | 2010 | WP_267811135.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| AB3428_RS11380 (AB3428_11380) | mecR1 | 2284010..2285767 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| AB3428_RS11385 (AB3428_11385) | mecI | 2285767..2286138 (+) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| AB3428_RS11390 (AB3428_11390) | psm-mec | 2286223..2286291 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| AB3428_RS11395 (AB3428_11395) | - | 2286625..2287755 (+) | 1131 | WP_010922808.1 | ROK family transcriptional regulator | - |
| AB3428_RS11400 (AB3428_11400) | cstB | 2287869..2289203 (-) | 1335 | Protein_2214 | persulfide dioxygenase-sulfurtransferase CstB | - |
| AB3428_RS11405 (AB3428_11405) | - | 2289236..2290300 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| AB3428_RS11410 (AB3428_11410) | cstR | 2290436..2290696 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| AB3428_RS11415 (AB3428_11415) | - | 2290696..2291334 (+) | 639 | Protein_2217 | sulfite exporter TauE/SafE family protein | - |
| AB3428_RS11420 (AB3428_11420) | - | 2291385..2291447 (-) | 63 | Protein_2218 | DNA repair protein RadC | - |
| AB3428_RS11425 (AB3428_11425) | - | 2291679..2292341 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| AB3428_RS11430 (AB3428_11430) | - | 2292733..2292792 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| AB3428_RS11435 (AB3428_11435) | erm(A) | 2292850..2293581 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| AB3428_RS11440 (AB3428_11440) | - | 2293707..2294489 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| AB3428_RS11445 (AB3428_11445) | - | 2294640..2295017 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| AB3428_RS11450 (AB3428_11450) | - | 2295024..2296916 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| AB3428_RS11455 (AB3428_11455) | - | 2296913..2297998 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| AB3428_RS11460 (AB3428_11460) | - | 2298117..2298434 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| AB3428_RS11465 (AB3428_11465) | - | 2298455..2298961 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| AB3428_RS11470 (AB3428_11470) | - | 2298979..2299290 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| AB3428_RS11475 (AB3428_11475) | - | 2299377..2299727 (-) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| AB3428_RS11480 (AB3428_11480) | ccrB | 2300245..2301873 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| AB3428_RS11485 (AB3428_11485) | ccrA | 2301895..2303244 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| AB3428_RS11490 (AB3428_11490) | - | 2303478..2305271 (-) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| AB3428_RS11495 (AB3428_11495) | - | 2305271..2305567 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| AB3428_RS11500 (AB3428_11500) | - | 2305760..2306806 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| AB3428_RS11505 (AB3428_11505) | - | 2307057..2308198 (-) | 1142 | Protein_2235 | IS3-like element ISSau4 family transposase | - |
| AB3428_RS11510 (AB3428_11510) | - | 2308709..2309635 (-) | 927 | Protein_2236 | YfcC family protein | - |
| AB3428_RS11515 (AB3428_11515) | - | 2310357..2311052 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| AB3428_RS11520 (AB3428_11520) | - | 2311027..2313696 (-) | 2670 | WP_000446429.1 | sensor histidine kinase KdpD | - |
| AB3428_RS11525 (AB3428_11525) | kdpF | 2313863..2313943 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| AB3428_RS11530 (AB3428_11530) | kdpA | 2313964..2315640 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| AB3428_RS11535 (AB3428_11535) | - | 2315659..2317680 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| AB3428_RS11540 (AB3428_11540) | - | 2317696..2318252 (+) | 557 | Protein_2242 | K(+)-transporting ATPase subunit C | - |
| AB3428_RS11545 (AB3428_11545) | - | 2318797..2319666 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| AB3428_RS11550 (AB3428_11550) | - | 2319676..2320572 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| AB3428_RS11555 (AB3428_11555) | - | 2321691..2322317 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| AB3428_RS11560 (AB3428_11560) | - | 2322432..2323940 (+) | 1509 | WP_341262107.1 | protein kinase | - |
| AB3428_RS11565 (AB3428_11565) | - | 2324190..2324324 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| AB3428_RS11570 (AB3428_11570) | - | 2324288..2324380 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| AB3428_RS11575 (AB3428_11575) | - | 2324527..2326272 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| AB3428_RS11580 (AB3428_11580) | - | 2326370..2326725 (-) | 356 | Protein_2250 | tRNA-dihydrouridine synthase | - |
| AB3428_RS11585 (AB3428_11585) | - | 2327030..2327118 (-) | 89 | Protein_2251 | hypothetical protein | - |
| AB3428_RS11590 (AB3428_11590) | - | 2327216..2327971 (-) | 756 | WP_031794076.1 | sulfite exporter TauE/SafE family protein | - |
| AB3428_RS11595 (AB3428_11595) | cstR | 2327971..2328231 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| AB3428_RS11600 (AB3428_11600) | cstA | 2328368..2329432 (+) | 1065 | WP_000816133.1 | persulfide response sulfurtransferase CstA | - |
| AB3428_RS11605 (AB3428_11605) | cstB | 2329463..2330797 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| AB3428_RS11610 (AB3428_11610) | sqr | 2330816..2332009 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| AB3428_RS11615 (AB3428_11615) | - | 2332276..2332490 (-) | 215 | Protein_2257 | universal stress protein | - |
| AB3428_RS11620 (AB3428_11620) | - | 2332676..2333662 (-) | 987 | WP_000662022.1 | tRNA-dihydrouridine synthase | - |
| AB3428_RS11625 (AB3428_11625) | - | 2333971..2334174 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| AB3428_RS11630 (AB3428_11630) | - | 2334223..2334519 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| AB3428_RS11635 (AB3428_11635) | - | 2334727..2335329 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| AB3428_RS11640 (AB3428_11640) | - | 2335596..2338748 (+) | 3153 | WP_000080564.1 | ATP-binding protein | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=1025307 AB3428_RS11480 WP_001186602.1 2300245..2301873(-) (ccrB) [Staphylococcus aureus strain TUM22707]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=1025307 AB3428_RS11480 WP_001186602.1 2300245..2301873(-) (ccrB) [Staphylococcus aureus strain TUM22707]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |