Detailed information NTG1025303

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3428_RS10730
• Genome accession: NZ_CP162428
• Coordinates: 2133601..2134488 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain TUM22707
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2128601..2139488

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3428_RS10700 (AB3428_10700)	-	2128620..2128712 (+)	93	WP_010956583.1	hypothetical protein	-
AB3428_RS10705 (AB3428_10705)	-	2128820..2129317 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3428_RS10710 (AB3428_10710)	-	2129327..2129587 (-)	261	WP_001791974.1	hypothetical protein	-
AB3428_RS10715 (AB3428_10715)	-	2129969..2130082 (-)	114	Protein_2079	hypothetical protein	-
AB3428_RS10720 (AB3428_10720)	-	2130741..2132741 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB3428_RS10725 (AB3428_10725)	-	2132738..2133493 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3428_RS10730 (AB3428_10730)	braS	2133601..2134488 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3428_RS10735 (AB3428_10735)	braR	2134499..2135164 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3428_RS10740 (AB3428_10740)	-	2135190..2135390 (-)	201	WP_000604730.1	hypothetical protein	-
AB3428_RS10745 (AB3428_10745)	-	2135588..2137012 (+)	1425	WP_000953755.1	alkaline phosphatase	-
AB3428_RS10750 (AB3428_10750)	-	2137072..2137173 (-)	102	WP_000731976.1	SE2200 family small protein	-
AB3428_RS10755 (AB3428_10755)	-	2137295..2137750 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3428_RS10760 (AB3428_10760)	-	2137995..2138756 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025303 AB3428_RS10730 WP_000143425.1 2133601..2134488(-) (braS) [Staphylococcus aureus strain TUM22707]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025303 AB3428_RS10730 WP_000143425.1 2133601..2134488(-) (braS) [Staphylococcus aureus strain TUM22707]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1