Detailed information NTG1025220

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3445_RS10885
• Genome accession: NZ_CP162422
• Coordinates: 2205574..2206461 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain TUM22723
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2200574..2211461

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3445_RS10855 (AB3445_10860)	-	2201306..2202067 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
AB3445_RS10860 (AB3445_10865)	-	2202312..2202767 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3445_RS10865 (AB3445_10870)	-	2202889..2202990 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3445_RS10870 (AB3445_10875)	-	2203050..2204474 (-)	1425	WP_000953744.1	alkaline phosphatase	-
AB3445_RS10875 (AB3445_10880)	-	2204672..2204872 (+)	201	WP_000604728.1	hypothetical protein	-
AB3445_RS10880 (AB3445_10885)	braR	2204898..2205563 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3445_RS10885 (AB3445_10890)	braS	2205574..2206461 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3445_RS10890 (AB3445_10895)	-	2206569..2207324 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3445_RS10895 (AB3445_10900)	-	2207321..2209321 (+)	2001	WP_000776751.1	ABC transporter permease	-
AB3445_RS10900 (AB3445_10905)	-	2209980..2210093 (+)	114	WP_011447078.1	hypothetical protein	-
AB3445_RS10905 (AB3445_10910)	-	2210475..2210735 (+)	261	WP_001789910.1	hypothetical protein	-
AB3445_RS10910 (AB3445_10915)	-	2210745..2211242 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3445_RS10915 (AB3445_10920)	-	2211350..2211442 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1025220 AB3445_RS10885 WP_000143419.1 2205574..2206461(+) (braS) [Staphylococcus aureus strain TUM22723]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025220 AB3445_RS10885 WP_000143419.1 2205574..2206461(+) (braS) [Staphylococcus aureus strain TUM22723]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997