Detailed information NTG1025182

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3453_RS13595
• Genome accession: NZ_CP162420
• Coordinates: 2714795..2715682 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22741
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2709795..2720682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3453_RS13565 (AB3453_13565)	-	2710527..2711288 (+)	762	Protein_2630	alpha/beta hydrolase	-
AB3453_RS13570 (AB3453_13570)	-	2711533..2711988 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3453_RS13575 (AB3453_13575)	-	2712110..2712211 (+)	102	WP_000731972.1	SE2200 family small protein	-
AB3453_RS13580 (AB3453_13580)	-	2712271..2713695 (-)	1425	WP_000953748.1	alkaline phosphatase	-
AB3453_RS13585 (AB3453_13585)	-	2713893..2714093 (+)	201	WP_000604727.1	hypothetical protein	-
AB3453_RS13590 (AB3453_13590)	braR	2714119..2714784 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3453_RS13595 (AB3453_13595)	braS	2714795..2715682 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3453_RS13600 (AB3453_13600)	-	2715790..2716545 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3453_RS13605 (AB3453_13605)	-	2716542..2718542 (+)	2001	WP_000776740.1	ABC transporter permease	-
AB3453_RS13610 (AB3453_13610)	-	2719201..2719314 (+)	114	Protein_2639	hypothetical protein	-
AB3453_RS13615 (AB3453_13615)	-	2719696..2719956 (+)	261	WP_001791974.1	hypothetical protein	-
AB3453_RS13620 (AB3453_13620)	-	2719966..2720463 (+)	498	WP_001065268.1	glutathione peroxidase	-
AB3453_RS13625 (AB3453_13625)	-	2720571..2720663 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1025182 AB3453_RS13595 WP_000143417.1 2714795..2715682(+) (braS) [Staphylococcus aureus strain TUM22741]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025182 AB3453_RS13595 WP_000143417.1 2714795..2715682(+) (braS) [Staphylococcus aureus strain TUM22741]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99