Detailed information NTG1025144

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: AB3453_RS02800
• Genome accession: NZ_CP162420
• Coordinates: 542558..543601 (+)
• Length: 347 a.a.
• NCBI ID: WP_267830476.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain TUM22741
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 537558..548601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3453_RS02770 (AB3453_02770)	-	537924..538035 (+)	112	Protein_539	hypothetical protein	-
AB3453_RS02775 (AB3453_02775)	-	538064..538477 (+)	414	WP_001837236.1	hypothetical protein	-
AB3453_RS02780 (AB3453_02780)	-	538967..539953 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
AB3453_RS02785 (AB3453_02785)	map	540484..541242 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
AB3453_RS02790 (AB3453_02790)	-	541459..541845 (+)	387	WP_001110179.1	hypothetical protein	-
AB3453_RS02795 (AB3453_02795)	liaF	541860..542561 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
AB3453_RS02800 (AB3453_02800)	vraS	542558..543601 (+)	1044	WP_267830476.1	sensor histidine kinase	Regulator
AB3453_RS02805 (AB3453_02805)	vraR	543591..544220 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
AB3453_RS02810 (AB3453_02810)	-	544332..545543 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
AB3453_RS02815 (AB3453_02815)	-	545821..546096 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
AB3453_RS02820 (AB3453_02820)	-	546103..546567 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
AB3453_RS02825 (AB3453_02825)	-	546714..546914 (+)	201	WP_000180460.1	DUF1128 family protein	-
AB3453_RS02830 (AB3453_02830)	-	546917..548173 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40078.54 Da
• Isoelectric Point: 6.0577

>NTDB_id=1025144 AB3453_RS02800 WP_267830476.1 542558..543601(+) (vraS) [Staphylococcus aureus strain TUM22741]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFFFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1025144 AB3453_RS02800 WP_267830476.1 542558..543601(+) (vraS) [Staphylococcus aureus strain TUM22741]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTTTTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997