Detailed information NTG1025104

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB3454_RS04375
• Genome accession: NZ_CP162418
• Coordinates: 815731..816618 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain TUM22750
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 810731..821618

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB3454_RS04345 (AB3454_04345)	-	810751..810843 (+)	93	WP_010956583.1	hypothetical protein	-
AB3454_RS04350 (AB3454_04350)	-	810951..811448 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB3454_RS04355 (AB3454_04355)	-	811458..811718 (-)	261	WP_001791974.1	hypothetical protein	-
AB3454_RS04360 (AB3454_04360)	-	812100..812213 (-)	114	Protein_818	hypothetical protein	-
AB3454_RS04365 (AB3454_04365)	-	812871..814871 (-)	2001	WP_000776740.1	ABC transporter permease	-
AB3454_RS04370 (AB3454_04370)	-	814868..815623 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB3454_RS04375 (AB3454_04375)	braS	815731..816618 (-)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB3454_RS04380 (AB3454_04380)	braR	816629..817294 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB3454_RS04385 (AB3454_04385)	-	817320..817520 (-)	201	WP_000604727.1	hypothetical protein	-
AB3454_RS04390 (AB3454_04390)	-	817718..819142 (+)	1425	WP_000953748.1	alkaline phosphatase	-
AB3454_RS04395 (AB3454_04395)	-	819202..819303 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB3454_RS04400 (AB3454_04400)	-	819425..819880 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB3454_RS04405 (AB3454_04405)	-	820125..820886 (-)	762	Protein_827	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=1025104 AB3454_RS04375 WP_000143417.1 815731..816618(-) (braS) [Staphylococcus aureus strain TUM22750]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1025104 AB3454_RS04375 WP_000143417.1 815731..816618(-) (braS) [Staphylococcus aureus strain TUM22750]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99