Detailed information NTG1024746

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQN42_RS08335
• Genome accession: NZ_LS483436
• Coordinates: 1692077..1694206 (-)
• Length: 709 a.a.
• NCBI ID: WP_003075813.1
• Uniprot ID: -
• Organism: Streptococcus intermedius strain NCTC11324
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1687077..1699206

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN42_RS08305 (NCTC11324_01672)	-	1687161..1687868 (-)	708	WP_003075831.1	L-ribulose-5-phosphate 4-epimerase	-
DQN42_RS08310 (NCTC11324_01673)	-	1687871..1688734 (-)	864	WP_003076035.1	L-ribulose-5-phosphate 3-epimerase	-
DQN42_RS08315 (NCTC11324_01674)	-	1688740..1689405 (-)	666	WP_003075923.1	3-keto-L-gulonate-6-phosphate decarboxylase UlaD	-
DQN42_RS08320 (NCTC11324_01675)	-	1689451..1689936 (-)	486	WP_003076136.1	PTS sugar transporter subunit IIA	-
DQN42_RS08325 (NCTC11324_01676)	-	1690138..1690419 (-)	282	WP_003074022.1	PTS sugar transporter subunit IIB	-
DQN42_RS08330 (NCTC11324_01677)	-	1690450..1691910 (-)	1461	WP_003075927.1	PTS ascorbate transporter subunit IIC	-
DQN42_RS08335 (NCTC11324_01678)	clpE	1692077..1694206 (-)	2130	WP_003075813.1	AAA family ATPase	Regulator
DQN42_RS08340 (NCTC11324_01679)	glmS	1694625..1696439 (-)	1815	WP_003076077.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
DQN42_RS08345 (NCTC11324_01680)	-	1696821..1698020 (-)	1200	WP_003076127.1	acetate kinase	-
DQN42_RS08350 (NCTC11324_01681)	comGH	1698067..1699020 (-)	954	WP_003075742.1	class I SAM-dependent methyltransferase	Machinery gene

Sequence

Protein

• Length: 709 a.a.
• Molecular weight: 78924.17 Da
• Isoelectric Point: 4.8757

>NTDB_id=1024746 DQN42_RS08335 WP_003075813.1 1692077..1694206(-) (clpE) [Streptococcus intermedius strain NCTC11324]
MNNNYNNFDNMDDLFNQLMGRMGGFNSENRRYLINGREVTPEEFAQYRATGKLPKQVAEGQASQMQGQAGELKQDGILMK
LGRNLTEEARQDMLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDIS
GLEAGTQYRGSFEENIQNLVSEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAEDTYKILQGIRDLYEKHHNVILPDDVLKAAVDFSIQYIPQRSLPDKAIDLVDVTAAHL
AAQHPVTDVHTVEREIAEQKKKQEAAVEKEDFETALNAKMRIEELEKKIENHTEDMKVTATVNDVAESVERMTGIPVSQM
GTSDIERLKEMNARLKTKVIGQNEAVEAVARAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKEAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFK
NTVIIATSNAGFGYESFTGDEEKDRKIIDRLKPYFRPEFLNRFNAVIEFSHLGKEDLAEIVDLMLDEVNQTLAKKDIMLT
VTDAAKHYLAEEGYDEVMGVRPLRRVIEQQIRDKVTDYHLDHLDAKHLLADLKDDELVIKEAKEHQTKK

Nucleotide

• Length: 2130 bp

>NTDB_id=1024746 DQN42_RS08335 WP_003075813.1 1692077..1694206(-) (clpE) [Streptococcus intermedius strain NCTC11324]
ATGAATAATAATTATAACAACTTTGATAATATGGATGATCTTTTCAATCAATTGATGGGAAGGATGGGCGGTTTTAACAG
TGAAAATCGGCGTTATCTTATCAATGGACGTGAAGTGACACCGGAAGAATTTGCACAATATCGTGCAACAGGTAAATTAC
CGAAGCAAGTAGCGGAAGGTCAGGCATCACAAATGCAAGGACAAGCAGGTGAGCTTAAACAAGATGGTATTTTAATGAAG
TTAGGGCGTAATTTGACAGAAGAAGCACGTCAAGATATGTTAGATCCTGTTATTGGACGCAATAAGGAAATTCAAGAAAC
GGCTGAAATTCTTTCTCGGCGGACGAAAAACAATCCAGTATTAGTCGGAGACGCTGGAGTTGGTAAGACTGCAGTTGTCG
AAGGTTTAGCGCAAGCGATTGTTAATGGAGATGTTCCTGCAGCCATTAAGAATAAAGAGATTGTTTCTATTGATATTTCT
GGTTTAGAAGCAGGGACACAGTATCGTGGTAGTTTTGAAGAAAATATTCAAAATTTAGTATCTGAAGTGAAAGAGGCTGG
CAATATCATTCTCTTCTTTGATGAAATTCATCAAATTCTCGGTGCTGGAAGCACAGGCGGTGATAGTGGATCAAAAGGTT
TAGCAGATATTTTGAAACCGGCTTTATCTCGTGGTGAACTGACAGTTATCGGTGCGACGACTCAGGATGAATATCGAAAT
ACCATTTTGAAGAATGCAGCTCTAGCTCGTCGCTTCAATGAAGTAAAAGTCAATGCCCCATCTGCAGAAGATACTTACAA
GATTTTGCAAGGAATTCGTGATTTATACGAAAAACACCACAATGTCATCTTGCCAGATGACGTGTTAAAAGCTGCCGTGG
ATTTCTCTATTCAATACATTCCGCAACGTAGCTTGCCGGATAAAGCGATTGACCTGGTGGATGTGACAGCGGCTCATTTA
GCAGCTCAACATCCTGTTACAGATGTGCATACAGTGGAACGTGAAATTGCAGAGCAAAAGAAAAAGCAAGAAGCTGCGGT
TGAAAAAGAAGACTTTGAAACTGCTTTGAATGCCAAGATGCGTATTGAAGAGCTAGAAAAAAAGATTGAAAATCATACGG
AAGACATGAAGGTGACTGCAACTGTCAATGATGTAGCAGAATCTGTAGAACGTATGACGGGCATTCCTGTTTCCCAAATG
GGGACTAGTGATATTGAACGGTTGAAAGAGATGAATGCGCGATTGAAGACAAAAGTCATTGGACAAAACGAAGCAGTTGA
AGCAGTGGCGCGCGCTATTCGTCGGAATCGTGCAGGTTTTGATGAAGGAAATCGTCCGATTGGTAGCTTTCTCTTTGTTG
GCCCAACTGGTGTTGGAAAAACAGAGCTAGCGAAGCAATTGGCGCTTGATATGTTTGGTACTAAAGAAGCTATTATCCGT
TTGGACATGTCTGAATACTCTGACCGCACAGCTGTGTCGAAATTGATTGGTACAACAGCTGGTTATGTGGGGTATGATGA
CAATAGTAACACGTTGACAGAACGTGTTCGTCGGAATCCTTACTCTATCATCTTGCTGGACGAAATTGAAAAAGCCGATC
CGCAAGTCATCACGCTGTTACTACAAGTTTTAGATGATGGACGTCTGACAGATGGACAAGGAAATACTGTCAACTTTAAG
AATACAGTTATTATTGCTACATCAAATGCTGGATTTGGGTATGAAAGCTTTACTGGTGATGAGGAAAAGGATAGGAAGAT
TATCGATCGCTTAAAACCATACTTCCGTCCAGAATTCTTGAATCGCTTCAATGCAGTCATTGAATTCTCTCATCTTGGTA
AAGAAGATTTAGCTGAAATCGTCGACTTGATGTTGGATGAGGTCAACCAAACACTTGCTAAGAAAGACATTATGCTAACA
GTAACAGATGCGGCCAAACATTATCTAGCAGAAGAGGGATATGATGAAGTTATGGGTGTTCGTCCGCTTCGTCGTGTGAT
TGAGCAACAAATCCGTGATAAGGTAACAGACTATCATCTTGATCATTTAGATGCGAAACATCTTCTTGCAGATTTGAAAG
ATGATGAATTAGTTATCAAAGAAGCGAAAGAGCATCAAACTAAAAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (261-356)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-605)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-682)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.262	100	0.463
clpC	Lactococcus lactis subsp. cremoris KW2	51.347	88.999	0.457
clpE	Streptococcus pneumoniae R6	45.035	100	0.454
clpE	Streptococcus pneumoniae D39	45.035	100	0.454
clpE	Streptococcus pneumoniae Rx1	45.035	100	0.454
clpE	Streptococcus pneumoniae TIGR4	44.803	100	0.45
clpC	Bacillus subtilis subsp. subtilis str. 168	47.214	91.114	0.43
clpC	Streptococcus pneumoniae Rx1	42.613	90.691	0.386
clpC	Streptococcus pneumoniae D39	42.613	90.691	0.386
clpC	Streptococcus pneumoniae TIGR4	42.457	90.691	0.385
clpC	Streptococcus mutans UA159	43.76	87.024	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.506	86.883	0.378
clpC	Streptococcus thermophilus LMD-9	42.626	87.024	0.371
clpC	Streptococcus thermophilus LMG 18311	42.464	87.024	0.37