Detailed information NTG1024703

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: AB1F57_RS10230
• Genome accession: NZ_CP162268
• Coordinates: 2018968..2021220 (+)
• Length: 750 a.a.
• NCBI ID: WP_367985707.1
• Uniprot ID: -
• Organism: Streptococcus sp. ZY1909104
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 2013968..2026220

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB1F57_RS10205 (AB1F57_10205)	-	2014442..2015365 (+)	924	WP_367985705.1	neutral zinc metallopeptidase	-
AB1F57_RS10210 (AB1F57_10210)	-	2016010..2016855 (-)	846	WP_367985706.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
AB1F57_RS10215 (AB1F57_10215)	-	2016970..2017704 (-)	735	WP_105110193.1	amino acid ABC transporter ATP-binding protein	-
AB1F57_RS10220 (AB1F57_10220)	-	2017706..2018386 (-)	681	WP_105136832.1	amino acid ABC transporter permease	-
AB1F57_RS10225 (AB1F57_10225)	-	2018514..2018744 (-)	231	WP_105123499.1	DUF1797 family protein	-
AB1F57_RS10230 (AB1F57_10230)	clpE	2018968..2021220 (+)	2253	WP_367985707.1	AAA family ATPase	Regulator
AB1F57_RS10235 (AB1F57_10235)	-	2021389..2022387 (-)	999	WP_167786309.1	MBL fold metallo-hydrolase	-
AB1F57_RS10240 (AB1F57_10240)	-	2022544..2023008 (+)	465	WP_105136829.1	NUDIX hydrolase	-
AB1F57_RS10245 (AB1F57_10245)	-	2023063..2023371 (+)	309	WP_167786308.1	DUF1827 family protein	-

Sequence

Protein

• Length: 750 a.a.
• Molecular weight: 83216.59 Da
• Isoelectric Point: 5.1535

>NTDB_id=1024703 AB1F57_RS10230 WP_367985707.1 2018968..2021220(+) (clpE) [Streptococcus sp. ZY1909104]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDFNPNNMDPFSEFFNHLGGYPNNTPAGRDRN
QTPPTQSGGGNRGGGRSNQPGGGIPQAPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQNKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRKEVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQAKYQDYHHVKYSD
QAIEAAVVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYK
EMQQATISEEDIPLITEKEIEAIIEQKTNIPVGDLKEKEQSQLINLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGAPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRAQSVLGQLGNFFSPEFMN
RFDGIIEFQPLSKDNLLEIVSLMLEDVNKRLSANGISLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLE
HPTEKNLRAVMSSKGDIQIKAQTVAKVKEV

Nucleotide

• Length: 2253 bp

>NTDB_id=1024703 AB1F57_RS10230 WP_367985707.1 2018968..2021220(+) (clpE) [Streptococcus sp. ZY1909104]
ATGCTCTGCAAAAACTGTAACATCAATGACGCAACCATCCATCTCTACACCAACCTCAACGGCAAACAACAGCAGGTCGA
CCTCTGCCACAACTGCTACCAAATCATGAAGACTGACCCCAACAACGCCATTCTCCGTGGCCTAGGCGATTTCAACCCTA
ACAACATGGATCCCTTCAGTGAATTTTTCAATCATTTGGGAGGATACCCTAACAACACACCAGCTGGACGTGACCGCAAC
CAGACACCTCCGACCCAGTCTGGAGGAGGGAACCGAGGCGGCGGCCGCTCCAATCAGCCTGGCGGAGGTATCCCGCAAGC
ACCGCAACAGCCAAACGGCCTCTTGGAAGAATTTGGTATTAACGTGACCGAGATTGCTCGTCGTGGAGATATTGACCCGG
TTATCGGACGCGACCAAGAAATCACTCGCGTAATTGAGATTCTCAACCGCCGGACCAAGAACAACCCCGTCCTCATCGGT
GAGCCCGGTGTTGGTAAAACGGCCGTTGTCGAAGGTCTGGCCCAGAAAATCGTAGACGGAGATGTCCCACATAAACTCCA
AAATAAGGAAGTTATCCGCCTAGACGTTGTTAGCTTAGTGCAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGC
AAAAACTAATGGAGGAAATTCGCAACCGTAAGGAAGTCATTCTCTTTATCGACGAAATCCATGAAATTGTCGGAGCAGGT
TCTGCTGGCGACGGCAACATGGATGCCGGCAACATTCTCAAACCAGCTCTTGCCCGTGGCGAAATGCAACTGGTCGGAGC
AACCACCCTCAATGAATACCGTATTATCGAGAAGGACGCCGCCTTGGAACGACGCATGCAACCTGTCAAGGTTGAGGAGC
CAAGCGTCGAAGAGACCATTACCATTCTCAAGGGCATCCAGGCTAAGTACCAGGACTACCACCACGTTAAGTATTCAGAT
CAGGCTATTGAAGCTGCAGTTGTCCTTTCCAACCGCTACATCCAGGACCGATTCCTGCCTGACAAGGCCATTGACCTCTT
GGATGAGGCGGGTTCCAAGATGAACCTGACCCTCAATTTCATTGATCCGAAAGAGATTGACCAACGCCTGATCGATGCTG
AAAATCGCAAAGCCCAAGCTACTCGTGATGAAGACTACGAAAAAGCTGCTTACTTCCGCGACCAGATTGCTAAATACAAG
GAAATGCAGCAGGCGACAATCAGTGAAGAGGACATTCCACTCATTACTGAGAAGGAAATCGAGGCCATTATCGAGCAGAA
AACCAATATTCCTGTCGGCGATTTGAAGGAGAAAGAACAATCTCAACTCATCAACCTAGCTAGCGACCTCAAGGCTCATG
TGATTGGCCAAGACGATGCCGTGGATAAGATTGCCAAGGCCATTCGTCGCAATCGCGTCGGATTGGGTGCGCCCAACCGT
CCAATCGGTTCCTTCCTCTTCGTTGGTCCAACCGGTGTCGGTAAGACCGAGCTTTCTAAACAGCTGGCCATCGAGCTCTT
CGGCTCAGCTGATAGTATGATTCGCTTTGATATGTCTGAGTACATGGAAAAACACGCCGTTGCCAAATTGGTCGGTGCCC
CTCCAGGTTATGTCGGCTATGAAGAGGCCGGGCAATTGACTGAGAAAGTGCGCCGCAATCCCTACTCGCTCATTCTCCTG
GATGAGGTAGAAAAGGCCCATCCAGATGTCATGCACATGTTCTTGCAGGTCCTGGATGACGGTCGCTTGACAGACGGTCA
AGGTCGGACTGTTTCCTTCAAAGATACTATCATTATCATGACCTCCAATGCCGGTACTGGCAAGGTTGAGGCCTCTGTCG
GTTTCGGTGCTGCTATGGAAGGGCGGGCTCAATCAGTCCTCGGTCAGCTTGGTAACTTCTTCAGCCCAGAATTTATGAAC
CGTTTCGACGGTATCATCGAATTCCAGCCGCTTAGTAAGGATAATCTGCTTGAAATTGTCAGCCTCATGCTGGAAGATGT
CAACAAGCGCTTGTCTGCCAACGGCATCAGCCTCCATGTGACAGACAAGGTCAAAGAAAAATTGGTCGACCTGGGCTATG
ATCCAAAAATGGGTGCCCGTCCGCTCCGCCGAACCATTCAAGACCAGATTGAAGATGCTATTACGGACTTCTATCTGGAA
CATCCAACGGAGAAAAATCTCCGCGCTGTCATGTCCAGCAAGGGAGACATTCAGATTAAGGCGCAAACCGTCGCCAAAGT
CAAAGAAGTCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (651-726)

• AAA lid domain (AAA_lid_9) (295-393)

• ATPase family associated with various cellular activities (AAA) (AAA) (157-276)

• AAA domain (Cdc48 subfamily) (AAA_2) (480-643)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.846	100	0.831
clpE	Streptococcus pneumoniae D39	82.846	100	0.831
clpE	Streptococcus pneumoniae R6	82.846	100	0.831
clpE	Streptococcus pneumoniae TIGR4	82.846	100	0.831
clpE	Streptococcus mutans UA159	82.603	100	0.829
clpC	Lactococcus lactis subsp. cremoris KW2	77.038	98.133	0.756
clpC	Bacillus subtilis subsp. subtilis str. 168	50.673	89.2	0.452
clpC	Streptococcus mutans UA159	48.315	83.067	0.401
clpC	Streptococcus pneumoniae Rx1	48.16	83.333	0.401
clpC	Streptococcus pneumoniae D39	48.16	83.333	0.401
clpC	Streptococcus pneumoniae TIGR4	48.16	83.333	0.401
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.875	85.333	0.4
clpC	Streptococcus thermophilus LMD-9	47.452	83.733	0.397
clpC	Streptococcus thermophilus LMG 18311	47.134	83.733	0.395