Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQN28_RS03765 Genome accession   NZ_LS483430
Coordinates   720506..720982 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC12044     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 715506..725982
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN28_RS03740 (NCTC12044_00737) - 715547..716335 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  DQN28_RS03745 (NCTC12044_00738) - 716375..717481 (+) 1107 WP_032462948.1 NAD(P)/FAD-dependent oxidoreductase -
  DQN28_RS03750 (NCTC12044_00739) rfbA 717539..718408 (+) 870 WP_111686248.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQN28_RS03755 (NCTC12044_00740) - 718408..719001 (+) 594 WP_002984882.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQN28_RS03760 (NCTC12044_00741) rfbB 719245..720285 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  DQN28_RS03765 (NCTC12044_00742) mutX 720506..720982 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQN28_RS03770 (NCTC12044_00743) - 721040..722221 (+) 1182 WP_002984879.1 AI-2E family transporter -
  DQN28_RS03775 (NCTC12044_00744) - 722211..723458 (+) 1248 WP_111686249.1 tetratricopeptide repeat protein -
  DQN28_RS03780 (NCTC12044_00745) fbp54 723517..725169 (-) 1653 WP_011054400.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1024454 DQN28_RS03765 WP_002984880.1 720506..720982(+) (mutX) [Streptococcus pyogenes strain NCTC12044]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1024454 DQN28_RS03765 WP_002984880.1 720506..720982(+) (mutX) [Streptococcus pyogenes strain NCTC12044]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703