Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQN31_RS00685 Genome accession   NZ_LS483421
Coordinates   104242..104526 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain NCTC10877     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99242..109526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN31_RS00660 (NCTC10877_00132) - 101202..101567 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQN31_RS00665 (NCTC10877_00133) comGA 101660..102584 (+) 925 Protein_81 competence type IV pilus ATPase ComGA -
  DQN31_RS00670 (NCTC10877_00134) comGB 102520..103554 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN31_RS00675 (NCTC10877_00135) comGC 103556..103882 (+) 327 WP_014407214.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN31_RS00680 (NCTC10877_00136) comGD 103857..104285 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN31_RS00685 (NCTC10877_00137) comGE 104242..104526 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQN31_RS00690 (NCTC10877_00138) comGF 104519..104953 (+) 435 WP_014407215.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN31_RS00695 (NCTC10877_00139) comGG 104937..105263 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQN31_RS00700 (NCTC10877_00140) comGH 105361..106314 (+) 954 WP_014407216.1 class I SAM-dependent methyltransferase Machinery gene
  DQN31_RS00705 (NCTC10877_00141) - 106373..107569 (+) 1197 WP_014407217.1 acetate kinase -
  DQN31_RS00710 - 107756..108064 (+) 309 WP_041174321.1 hypothetical protein -
  DQN31_RS00715 (NCTC10877_00142) proC 108147..108917 (-) 771 WP_014407219.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=1024177 DQN31_RS00685 WP_002987779.1 104242..104526(+) (comGE) [Streptococcus pyogenes strain NCTC10877]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1024177 DQN31_RS00685 WP_002987779.1 104242..104526(+) (comGE) [Streptococcus pyogenes strain NCTC10877]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTAAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383