Detailed information NTG1024172

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: QUR21_RS13865
• Genome accession: NZ_CP162115
• Coordinates: 2746383..2747270 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN12
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2741383..2752270

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QUR21_RS13835 (QUR21_13845)	-	2741402..2741494 (+)	93	WP_010956583.1	hypothetical protein	-
QUR21_RS13840 (QUR21_13850)	-	2741602..2742099 (-)	498	WP_001065268.1	glutathione peroxidase	-
QUR21_RS13845 (QUR21_13855)	-	2742109..2742369 (-)	261	WP_001791974.1	hypothetical protein	-
QUR21_RS13850 (QUR21_13860)	-	2742751..2742864 (-)	114	Protein_2690	hypothetical protein	-
QUR21_RS13855 (QUR21_13865)	-	2743523..2745523 (-)	2001	WP_000776754.1	ABC transporter permease	-
QUR21_RS13860 (QUR21_13870)	-	2745520..2746275 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
QUR21_RS13865 (QUR21_13875)	braS	2746383..2747270 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
QUR21_RS13870 (QUR21_13880)	braR	2747281..2747946 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
QUR21_RS13875 (QUR21_13885)	-	2747972..2748172 (-)	201	WP_000604730.1	hypothetical protein	-
QUR21_RS13880 (QUR21_13890)	-	2748370..2749794 (+)	1425	WP_000953755.1	alkaline phosphatase	-
QUR21_RS13885 (QUR21_13895)	-	2749854..2749955 (-)	102	WP_000731976.1	SE2200 family small protein	-
QUR21_RS13890 (QUR21_13900)	-	2750077..2750532 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
QUR21_RS13895 (QUR21_13905)	-	2750777..2751538 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1024172 QUR21_RS13865 WP_000143425.1 2746383..2747270(-) (braS) [Staphylococcus aureus strain BSN12]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1024172 QUR21_RS13865 WP_000143425.1 2746383..2747270(-) (braS) [Staphylococcus aureus strain BSN12]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1