Detailed information NTG1024167

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: QUR21_RS09980
• Genome accession: NZ_CP162115
• Coordinates: 2014297..2015340 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN12
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2009297..2020340

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QUR21_RS09950 (QUR21_09965)	-	2009718..2010974 (-)	1257	WP_001795108.1	aminopeptidase	-
QUR21_RS09955 (QUR21_09970)	-	2010977..2011177 (-)	201	WP_000180460.1	DUF1128 family protein	-
QUR21_RS09960 (QUR21_09975)	-	2011324..2011788 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
QUR21_RS09965 (QUR21_09980)	-	2011795..2012070 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
QUR21_RS09970 (QUR21_09985)	-	2012348..2013565 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
QUR21_RS09975 (QUR21_09990)	vraR	2013678..2014307 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
QUR21_RS09980 (QUR21_09995)	vraS	2014297..2015340 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
QUR21_RS09985 (QUR21_10000)	liaF	2015337..2016038 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
QUR21_RS09990 (QUR21_10005)	-	2016053..2016439 (-)	387	WP_001110179.1	hypothetical protein	-
QUR21_RS09995 (QUR21_10010)	map	2016656..2017414 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
QUR21_RS10000 (QUR21_10015)	-	2017945..2018931 (+)	987	WP_000999710.1	aromatic acid exporter family protein	-
QUR21_RS10005 (QUR21_10020)	-	2019362..2019775 (-)	414	WP_001557448.1	hypothetical protein	-
QUR21_RS10010 (QUR21_10025)	-	2019804..2019914 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1024167 QUR21_RS09980 WP_001017131.1 2014297..2015340(-) (vraS) [Staphylococcus aureus strain BSN12]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1024167 QUR21_RS09980 WP_001017131.1 2014297..2015340(-) (vraS) [Staphylococcus aureus strain BSN12]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1