Detailed information NTG1024072

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DQM62_RS09605
• Genome accession: NZ_LS483418
• Coordinates: 1915975..1918515 (-)
• Length: 846 a.a.
• NCBI ID: WP_012775399.1
• Uniprot ID: A0A0H3MXU9
• Organism: Streptococcus suis strain NCTC10234
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1910975..1923515

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM62_RS09585 (NCTC10234_01883)	-	1913337..1914626 (+)	1290	WP_012775456.1	IS4 family transposase	-
DQM62_RS09590 (NCTC10234_01884)	-	1914741..1914929 (-)	189	WP_014636177.1	hypothetical protein	-
DQM62_RS09595 (NCTC10234_01885)	-	1914963..1915403 (-)	441	WP_012027998.1	DUF3021 domain-containing protein	-
DQM62_RS09600 (NCTC10234_01886)	-	1915400..1915843 (-)	444	WP_012027999.1	LytTR family DNA-binding domain-containing protein	-
DQM62_RS09605 (NCTC10234_01887)	hexA	1915975..1918515 (-)	2541	WP_012775399.1	DNA mismatch repair protein MutS	Machinery gene
DQM62_RS09610 (NCTC10234_01888)	argR	1918530..1918970 (-)	441	WP_002937036.1	arginine repressor	-
DQM62_RS09615 (NCTC10234_01889)	argS	1919077..1920765 (+)	1689	WP_012028003.1	arginine--tRNA ligase	-
DQM62_RS09620 (NCTC10234_01890)	-	1920945..1921859 (+)	915	WP_012775400.1	SH3 domain-containing protein	-
DQM62_RS09625 (NCTC10234_01891)	-	1921912..1922433 (-)	522	WP_012775401.1	hypothetical protein	-
DQM62_RS09630 (NCTC10234_01892)	-	1922545..1922727 (+)	183	WP_002937045.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 95116.55 Da
• Isoelectric Point: 4.8252

>NTDB_id=1024072 DQM62_RS09605 WP_012775399.1 1915975..1918515(-) (hexA) [Streptococcus suis strain NCTC10234]
MATEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEDEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILQQINEPALGNLVAGLDPIPELHALISSAIDP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPDHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
DQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVIMAQMGSYVPADQAELPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQLDLFADTPSHPVLDELEKLDIYNMTPMEVMMAVAELKKKI

Nucleotide

• Length: 2541 bp

>NTDB_id=1024072 DQM62_RS09605 WP_012775399.1 1915975..1918515(-) (hexA) [Streptococcus suis strain NCTC10234]
ATGGCAACAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAATTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAATTGTCCTTGACCAGTC
GGAATAAGAATGCGGAAAATCCGATTCCCATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCACAAGGTCGCAATTGCCGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGACTCGTCCAAAATGGGAGCAGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTACAGTTCGCGCTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACTAGT
CTTTGCGGTGAGATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTTTATCTGAGGAAGAAGAGCAGGTCTT
TTCGAACCAGATGAACCTCCTGCTCTCTTTTGAGGATGAGGTGACGGAAGATGTCCAGCTGATTGACAACTCCTTGACAG
ACTTGGAAAAGGCTGCGGCAGGTAAACTCCTCAGCTACCTACATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCACTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCCAGTCTGGACCTGCTTGAAAACGGTCG
GACAGGCAAGAAGCATGGTAGTTTGTACTGGTTGCTAGACGAAACTAAGACAGCCATGGGTATGCGACTATTGCGGACAT
GGATTGATCGTCCCTTGATTGATCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGTTTGGCCAGCCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTTTGGGAAATATCCCAGCAATCAAGAATATCTTGCAACAAATCAATG
AGCCTGCTCTAGGCAATTTGGTGGCTGGATTGGACCCAATCCCAGAACTGCACGCTCTCATCAGCTCTGCTATTGACCCA
GAAGCCCAAGGGACCATCACAGATGGAAACATCATCCGTACAGGCTTTGACGAAACGCTGGATCAGTATCGTCTAGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCATCTGGTATCAATAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTCCATGTTACCAATTCCAATCTGGGCAATGTGCCGGACCATTTTTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATTGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATAGGTCGCTTGCAGAAGCTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCCTTTGCAGTTGTGGCGGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GATCAAAGAGAACTGACCATTGACCGTGGTCGTCATGCGGTGGTGGAGAAGGTCATGGGCAAGCAGACCTACATTCCCAA
CTCTATTCACTTGAATACCGATACACATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGAC
AGTTGGCGGTTATCGTCATCATGGCGCAGATGGGTTCCTATGTGCCTGCGGATCAGGCTGAATTACCGATTTTCGATGCT
ATTTTCACCCGAATTGGGGCGGCAGACGACTTGGTTAGTGGTCAATCGACCTTCATGGTCGAAATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGATGAGTTGGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCATGACAAGATTGGTGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTGGAACACTTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATTCATGTGGCTAAGATTGCGGGAATGCCAGAGGAACTAT
TGCAGCGGGCAGATCGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTAGTG
GAAGAACCGTCAGGTCAACTTGATCTCTTCGCAGACACGCCTTCTCACCCAGTACTTGATGAACTGGAAAAACTAGACAT
CTACAATATGACCCCTATGGAAGTCATGATGGCGGTGGCGGAGTTGAAGAAAAAAATATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

3D structure

• AlphaFold DB: A0A0H3MXU9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.877	100	0.739
mutS	Pseudomonas stutzeri strain ATCC 17587	37.762	100	0.383