Detailed information    

insolico Bioinformatically predicted

Overview

Name   cytR   Type   Regulator
Locus tag   ECRM12761_RS23150 Genome accession   NZ_CP007133
Coordinates   4556529..4557521 (+) Length   330 a.a.
NCBI ID   WP_000224470.1    Uniprot ID   P0ACQ1
Organism   Escherichia coli O145:H28 str. RM12761     
Function   promote competence gene expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 4551529..4562521
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECRM12761_RS23125 (ECRM12761_22470) rbsD 4551653..4552072 (+) 420 WP_000715936.1 D-ribose pyranase -
  ECRM12761_RS23130 (ECRM12761_22475) rbsA 4552080..4553585 (+) 1506 WP_000387770.1 ribose ABC transporter ATP-binding protein RbsA -
  ECRM12761_RS23135 (ECRM12761_22480) rbsC 4553590..4554555 (+) 966 WP_000211858.1 ribose ABC transporter permease -
  ECRM12761_RS23140 (ECRM12761_22485) rbsB 4554580..4555470 (+) 891 WP_001056273.1 ribose ABC transporter substrate-binding protein RbsB -
  ECRM12761_RS23145 (ECRM12761_22490) rbsK 4555596..4556525 (+) 930 WP_024221644.1 ribokinase -
  ECRM12761_RS23150 (ECRM12761_22495) cytR 4556529..4557521 (+) 993 WP_000224470.1 ribose operon transcriptional repressor RbsR Regulator
  ECRM12761_RS23155 (ECRM12761_22500) mdtD 4557499..4558914 (-) 1416 WP_001280851.1 multidrug transporter subunit MdtD -
  ECRM12761_RS23160 (ECRM12761_22505) yieP 4558937..4559629 (-) 693 WP_001131164.1 FadR/GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 330 a.a.        Molecular weight: 36611.90 Da        Isoelectric Point: 5.2141

>NTDB_id=102383 ECRM12761_RS23150 WP_000224470.1 4556529..4557521(+) (cytR) [Escherichia coli O145:H28 str. RM12761]
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA

Nucleotide


Download         Length: 993 bp        

>NTDB_id=102383 ECRM12761_RS23150 WP_000224470.1 4556529..4557521(+) (cytR) [Escherichia coli O145:H28 str. RM12761]
TTGGCTACAATGAAAGATGTTGCCCGCCTGGCGGGCGTTTCTACCTCAACAGTTTCTCACGTTATCAATAAAGATCGCTT
CGTCAGTGAAGCGATTACCGCCAAAGTTGAAGCGGCGATTAAAGAACTCAATTACGCGCCATCAGCTCTGGCGCGTAGCC
TCAAACTCAATCAAACACATACCATTGGCATGTTGATCACTGCCAGTACTAATCCTTTCTATTCAGAACTGGTGCGCGGC
GTTGAACGCAGCTGCTTCGAACGCGGTTATAGTCTTGTCCTTTGCAATACCGAAGGCGATGAACAGCGGATGAATCGCAA
TCTGGAAACGCTGATGCAAAAACGCGTTGATGGCTTGCTGTTACTGTGCACCGAAACGCATCAGCCTTCGCGTGAAATCA
TGCAGCGTTATCCGACAGTGCCTACCGTGATGATGGACTGGGCTCCGTTCGATGGCGACAGCGATCTTATTCAGGATAAC
TCGTTGCTGGGCGGAGACTTAGCAACGCAATATCTGATCGATAAAGGTCATACCCGTATCGCCTGTATTACCGGTCCGCT
GGATAAAACTCCGGCGCGCCTGCGGTTGGAAGGTTATCGGGCGGCGATGAAACGTGCGGGTCTCAACATTCCTGATGGCT
ATGAAGTCACTGGTGATTTTGAATTTAACGGCGGGTTTGACGCCATGCGCCAACTGTTATCACATCCGCTGCGTCCTCAG
GCCGTCTTTACCGGAAATGACGCTATGGCTGTTGGCGTTTACCAGGCGTTATATCAGGCAGAGTTACAGGTTCCGCAGGA
TATCGCGGTGATTGGCTATGACGATATCGAACTGGCAAGCTTTATGACGCCACCATTAACCACTATCCATCAACCGAAAG
ATGAACTGGGGGAGCTGGCGATTGATGTACTCATCCATCGGATAACCCAGCCGACCCTTCAGCAACAACGATTACAACTT
ACTCCGATTCTTATGGAACGCGGTTCGGCTTAG

Domains

Predicted by InterProScan.

Periplasmic binding protein-like domain (Peripla_BP_3)

(169-329)

Bacterial regulatory proteins, lacI family (LacI)

(3-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0ACQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cytR Vibrio parahaemolyticus RIMD 2210633

37.048

100

0.373
  cytR Vibrio cholerae C6706

39.088

93.03

0.364

Multiple sequence alignment