Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQN44_RS05825 Genome accession   NZ_LS483414
Coordinates   1125696..1126172 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC13736     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1120696..1131172
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN44_RS05810 (NCTC13736_01156) fbp54 1121508..1123160 (+) 1653 WP_030127490.1 Rqc2 family fibronectin-binding protein Fbp54 -
  DQN44_RS05815 (NCTC13736_01157) - 1123220..1124467 (-) 1248 WP_030126713.1 tetratricopeptide repeat protein -
  DQN44_RS05820 (NCTC13736_01158) - 1124457..1125638 (-) 1182 WP_030127489.1 AI-2E family transporter -
  DQN44_RS05825 (NCTC13736_01159) mutX 1125696..1126172 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQN44_RS05835 (NCTC13736_01160) speh 1126776..1127486 (-) 711 WP_010922229.1 streptococcal pyrogenic exotoxin SpeH -
  DQN44_RS05840 (NCTC13736_01161) spei 1127512..1128189 (-) 678 WP_047373492.1 streptococcal pyrogenic exotoxin SpeI -
  DQN44_RS05845 (NCTC13736_01162) - 1128463..1129797 (-) 1335 WP_011284838.1 GH25 family lysozyme -
  DQN44_RS05850 (NCTC13736_01164) - 1129909..1130094 (-) 186 WP_002990010.1 holin -
  DQN44_RS05855 (NCTC13736_01165) - 1130091..1130387 (-) 297 WP_002990012.1 hypothetical protein -
  DQN44_RS05860 (NCTC13736_01166) - 1130398..1131009 (-) 612 WP_011054733.1 DUF1366 domain-containing protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1023732 DQN44_RS05825 WP_002984880.1 1125696..1126172(-) (mutX) [Streptococcus pyogenes strain NCTC13736]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1023732 DQN44_RS05825 WP_002984880.1 1125696..1126172(-) (mutX) [Streptococcus pyogenes strain NCTC13736]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703