Detailed information    

insolico Bioinformatically predicted

Overview

Name   cqsS   Type   Regulator
Locus tag   ABU640_RS16790 Genome accession   NZ_CP161855
Coordinates   597701..599761 (+) Length   686 a.a.
NCBI ID   WP_080286462.1    Uniprot ID   -
Organism   Vibrio cholerae strain C3616     
Function   autoinducer sensor (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 568519..597604 597701..599761 flank 97


Gene organization within MGE regions


Location: 568519..599761
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABU640_RS16640 (ABU640_16640) - 568519..568932 (+) 414 WP_000451546.1 GNAT family N-acetyltransferase -
  ABU640_RS16645 (ABU640_16645) - 569093..569551 (+) 459 WP_000479509.1 CPBP family glutamic-type intramembrane protease -
  ABU640_RS16650 (ABU640_16650) - 569853..570032 (+) 180 WP_001893662.1 DUF645 family protein -
  ABU640_RS16655 (ABU640_16655) - 570243..570626 (+) 384 WP_001081298.1 hypothetical protein -
  ABU640_RS16660 (ABU640_16660) - 570746..571027 (+) 282 WP_080033233.1 DUF1289 domain-containing protein -
  ABU640_RS16665 (ABU640_16665) - 571406..572338 (+) 933 WP_001267735.1 hypothetical protein -
  ABU640_RS16670 (ABU640_16670) - 572322..572750 (+) 429 WP_000082746.1 hypothetical protein -
  ABU640_RS16675 (ABU640_16675) - 572968..573225 (+) 258 WP_000861987.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
  ABU640_RS16680 (ABU640_16680) - 573213..573515 (+) 303 WP_000818171.1 type II toxin-antitoxin system RelE/ParE family toxin -
  ABU640_RS16685 (ABU640_16685) - 574139..574792 (+) 654 WP_000132882.1 hypothetical protein -
  ABU640_RS16690 (ABU640_16690) - 574827..575464 (-) 638 Protein_550 IS30 family transposase -
  ABU640_RS16695 (ABU640_16695) - 575532..576709 (+) 1178 WP_086010043.1 IS3 family transposase -
  ABU640_RS16700 (ABU640_16700) - 576717..577046 (-) 330 Protein_552 transposase -
  ABU640_RS16705 (ABU640_16705) tnpA 577223..577660 (+) 438 WP_000503164.1 IS200/IS605-like element IS1004 family transposase -
  ABU640_RS16710 (ABU640_16710) - 577911..578408 (-) 498 WP_000982260.1 GNAT family N-acetyltransferase -
  ABU640_RS16715 (ABU640_16715) - 578405..578677 (-) 273 WP_000246253.1 DUF1778 domain-containing protein -
  ABU640_RS16720 (ABU640_16720) - 578889..579188 (-) 300 WP_001247271.1 type II toxin-antitoxin system RelE/ParE family toxin -
  ABU640_RS16725 (ABU640_16725) - 579185..579427 (-) 243 WP_001107716.1 type II toxin-antitoxin system ParD family antitoxin -
  ABU640_RS16730 (ABU640_16730) - 579518..579689 (-) 172 Protein_558 IS30 family transposase -
  ABU640_RS16735 (ABU640_16735) - 580016..582802 (+) 2787 WP_001966133.1 alkaline phosphatase family protein -
  ABU640_RS16740 (ABU640_16740) nrdD 583265..585385 (+) 2121 WP_000802768.1 anaerobic ribonucleoside-triphosphate reductase -
  ABU640_RS16745 (ABU640_16745) nrdG 585390..585857 (+) 468 WP_001106209.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
  ABU640_RS16750 (ABU640_16750) - 585979..587160 (+) 1182 WP_000494053.1 amino acid aminotransferase -
  ABU640_RS16755 (ABU640_16755) - 587218..587901 (+) 684 WP_000082071.1 ATP-dependent zinc protease -
  ABU640_RS16760 (ABU640_16760) fruA 588128..589864 (-) 1737 WP_000684713.1 PTS fructose transporter subunit IIBC -
  ABU640_RS16765 (ABU640_16765) pfkB 589883..590836 (-) 954 WP_000163395.1 1-phosphofructokinase -
  ABU640_RS16770 (ABU640_16770) fruB 590847..592049 (-) 1203 WP_000891932.1 fused PTS fructose transporter subunit IIA/HPr protein -
  ABU640_RS16775 (ABU640_16775) cra 592388..593368 (+) 981 WP_000171125.1 catabolite repressor/activator -
  ABU640_RS16780 (ABU640_16780) - 593422..594561 (+) 1140 WP_000670240.1 exonuclease SbcCD subunit D -
  ABU640_RS16785 (ABU640_16785) - 594563..597604 (+) 3042 WP_001247664.1 AAA family ATPase -
  ABU640_RS16790 (ABU640_16790) cqsS 597701..599761 (+) 2061 WP_080286462.1 quorum-sensing CAI-1 autoinducer sensor kinase/phosphatase CqsS Regulator

Sequence

Protein


Download         Length: 686 a.a.        Molecular weight: 78496.30 Da        Isoelectric Point: 5.3925

>NTDB_id=1022790 ABU640_RS16790 WP_080286462.1 597701..599761(+) (cqsS) [Vibrio cholerae strain C3616]
MIVSMDVIKRVYQYAEPNLFLVGWMGMLGFPAYYFIWEYWFPQSYENLGLRCAAAVLFGGLVFRDSMPKKWQRYMPGYFL
FTIGFCLPFFFAFMMLMNDWSTIWAMSFMASIFLHILLVHDTRVMALQALFSVLVAYLAVYGLTDFHPTTLIEWQYIPIF
LFTYVFGNLCFFRNQISHETKVSIAKTFGAGIAHEMRNPLSALKTSIDVVRTMIPKPQTAAHTDYSLDAQELDLLHQILN
EADDVIYSGNNAIDLLLTSIDENRVSPASFKKHSVVDVIEKAVKTFPYKNAADQHSVELEVHQPFDFFGSDTLLTYALFN
LLKNAFYYQKEHFSVRISIEQTSEHNLIRVRDNGVGIAPEMLEDIFRDFYTFGKNGSYGLGLPFCRKVMSAFGGTIRCAS
QQGQWTEFVLSFPRYDSDTVNEIKTELLKTKSLIYIGSNQAIVRELNQLAVEDEFGFTAISAQQAVRRQDYEFEFDLILL
DLDDATAQGELLPKLEGTLSFAEGCIGYVYDPGKTYAVNINRYLRIQPISIHSILRKPRKIIERLLFEQESLSMNRNVIP
LQKSRHERRILVVDDNQSIRTFTAILLEQQGYEVVQANDGSEVLKHMESQNIDLVLMDIEMPNVGGLEATRLIRDSEHEY
KNIPIIGYTGDNSPKTLALVQTSGMNDFIVKPADRDVLLNKVAAWV

Nucleotide


Download         Length: 2061 bp        

>NTDB_id=1022790 ABU640_RS16790 WP_080286462.1 597701..599761(+) (cqsS) [Vibrio cholerae strain C3616]
GTGATAGTGAGCATGGATGTAATAAAGAGAGTGTATCAATACGCAGAACCTAATCTGTTCTTAGTCGGATGGATGGGCAT
GCTTGGCTTTCCTGCCTACTACTTCATCTGGGAATATTGGTTTCCGCAATCTTACGAAAATTTAGGGCTGCGCTGTGCGG
CAGCAGTGCTGTTTGGTGGGCTGGTGTTTCGTGATTCGATGCCTAAGAAATGGCAGCGGTATATGCCGGGCTATTTTCTA
TTCACCATAGGTTTCTGCTTACCCTTTTTCTTCGCTTTTATGATGTTAATGAACGACTGGTCGACAATTTGGGCCATGTC
GTTTATGGCGTCCATTTTTCTGCATATTCTCTTAGTGCACGATACGAGAGTGATGGCGTTACAAGCTCTTTTCTCCGTGT
TGGTGGCCTATCTTGCGGTATATGGTTTGACGGATTTTCACCCGACGACTTTGATTGAATGGCAATACATACCGATCTTT
TTGTTTACTTATGTATTTGGGAATTTATGTTTTTTCCGTAACCAAATTTCTCATGAGACCAAAGTGTCGATTGCCAAAAC
GTTCGGAGCGGGGATTGCCCATGAAATGCGTAATCCACTCAGCGCTTTGAAAACGTCGATTGATGTTGTGCGAACCATGA
TCCCTAAACCGCAAACTGCAGCTCATACGGATTATTCCTTGGATGCGCAAGAGCTGGATCTGCTGCATCAAATTTTGAAT
GAAGCTGATGATGTCATCTACTCTGGCAATAACGCGATTGATTTGCTGCTCACCTCGATTGATGAAAACCGCGTCTCTCC
GGCGAGTTTTAAAAAACACTCCGTAGTGGATGTGATTGAAAAAGCGGTGAAAACTTTTCCGTATAAAAATGCAGCGGACC
AGCACTCGGTAGAGCTTGAAGTGCATCAGCCGTTTGACTTTTTTGGCAGTGATACTCTACTGACTTATGCGCTATTTAAC
CTGTTGAAAAATGCCTTTTATTATCAAAAAGAGCATTTTTCAGTTCGTATTTCCATTGAACAAACCAGTGAGCATAACCT
TATTCGAGTCCGTGATAACGGCGTGGGGATTGCGCCAGAGATGTTGGAAGACATTTTCCGTGATTTCTATACCTTCGGTA
AAAATGGCAGCTATGGGCTAGGATTGCCATTTTGCCGCAAAGTGATGTCCGCATTTGGGGGGACGATTCGCTGTGCGTCT
CAACAAGGTCAATGGACAGAATTCGTATTGAGCTTTCCTCGTTACGATTCCGATACGGTTAACGAGATAAAAACAGAACT
GCTGAAAACCAAATCGCTCATTTATATCGGCTCAAATCAAGCTATCGTTCGAGAGTTAAATCAGCTCGCAGTAGAAGATG
AGTTTGGTTTTACCGCTATTTCTGCGCAGCAAGCAGTAAGACGCCAAGATTATGAGTTTGAGTTCGACCTTATTTTGCTC
GACCTTGATGACGCTACGGCGCAGGGAGAACTACTGCCGAAACTTGAAGGGACATTGAGTTTTGCAGAAGGCTGTATCGG
CTATGTGTATGACCCGGGTAAAACGTACGCGGTAAACATTAACCGTTATCTGCGTATCCAACCGATCAGTATTCACTCTA
TTCTCAGAAAGCCGCGGAAAATCATCGAACGCTTGTTGTTTGAGCAAGAATCCTTATCGATGAATCGTAACGTGATCCCC
TTGCAAAAGAGTCGGCATGAACGACGTATTTTGGTGGTTGATGATAATCAATCGATCCGAACTTTTACGGCTATTTTGCT
TGAGCAACAAGGTTATGAAGTGGTGCAAGCCAACGATGGTAGTGAAGTGCTCAAGCATATGGAGAGTCAAAACATCGATT
TAGTGTTGATGGACATTGAAATGCCGAATGTCGGGGGATTAGAAGCGACGCGTTTAATTCGCGACTCTGAGCATGAATAT
AAAAATATTCCGATCATTGGTTACACTGGTGATAACAGCCCCAAAACCTTGGCTCTGGTACAAACCTCAGGCATGAATGA
TTTCATTGTGAAGCCTGCTGACCGTGATGTATTGCTAAATAAAGTGGCAGCTTGGGTGTAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(312-413)

Response regulator receiver domain (Response_reg)

(570-682)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cqsS Vibrio cholerae strain A1552

99.563

100

0.996

Multiple sequence alignment