Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   AB1395_RS02010 Genome accession   NZ_CP161815
Coordinates   378132..378821 (+) Length   229 a.a.
NCBI ID   WP_115129732.1    Uniprot ID   A0A345VI01
Organism   Streptococcus pluranimalium strain SS-15     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 373132..383821
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1395_RS01985 (AB1395_01985) - 373510..374181 (-) 672 WP_278024987.1 TrkA family potassium uptake protein -
  AB1395_RS01990 (AB1395_01990) - 374200..375573 (-) 1374 WP_218654044.1 TrkH family potassium uptake protein -
  AB1395_RS01995 (AB1395_01995) rsmG 375598..376311 (-) 714 WP_160545032.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  AB1395_RS02000 (AB1395_02000) htpX 376426..377331 (+) 906 WP_218654045.1 zinc metalloprotease HtpX -
  AB1395_RS02005 (AB1395_02005) - 377366..377899 (+) 534 WP_218654046.1 DUF177 domain-containing protein -
  AB1395_RS02010 (AB1395_02010) covR 378132..378821 (+) 690 WP_115129732.1 response regulator transcription factor Regulator
  AB1395_RS02015 (AB1395_02015) - 378865..380322 (+) 1458 WP_256866665.1 HAMP domain-containing histidine kinase -
  AB1395_RS02020 (AB1395_02020) nrdR 380766..381239 (+) 474 WP_104968798.1 transcriptional regulator NrdR -
  AB1395_RS02025 (AB1395_02025) - 381239..382411 (+) 1173 WP_104967320.1 DnaD domain protein -
  AB1395_RS02030 (AB1395_02030) dnaI 382414..383316 (+) 903 WP_218654048.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26370.19 Da        Isoelectric Point: 4.7749

>NTDB_id=1022579 AB1395_RS02010 WP_115129732.1 378132..378821(+) (covR) [Streptococcus pluranimalium strain SS-15]
MTKNILIIEDEKNLSRFVSLELQHEGYSVTIESNGRAGLETALDKDFDLILLDLMLPEMDGFEVTRRLQQEKSTYIIMMT
ARDSVMDIVSGLDRGADDYIIKPFAIEELLARVRAAFRRQEIEESKRNASGGASYRDLKLDPQNRSVIRGDETVPLTKRE
FDLLSALMSNMNRVMTREELLNLVWKYDEAVETNVVDVYIRYLRGKIDVSGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1022579 AB1395_RS02010 WP_115129732.1 378132..378821(+) (covR) [Streptococcus pluranimalium strain SS-15]
ATGACAAAAAATATTCTGATCATAGAGGATGAGAAAAATCTTTCGCGCTTCGTTTCTTTAGAATTACAGCATGAAGGGTA
TTCGGTAACCATTGAAAGTAATGGTCGCGCTGGTTTAGAAACAGCGTTAGATAAAGATTTTGATTTGATTTTATTAGACT
TGATGTTGCCAGAGATGGATGGCTTTGAAGTGACACGTCGCTTACAACAAGAAAAGTCAACTTACATCATTATGATGACT
GCTAGAGACTCTGTTATGGATATTGTTTCAGGATTGGATCGTGGCGCAGATGATTACATTATCAAGCCATTTGCGATTGA
GGAACTCTTAGCGCGTGTTCGTGCTGCTTTTCGTCGTCAAGAAATTGAAGAAAGTAAACGAAATGCTTCAGGTGGAGCTA
GCTATCGTGACCTCAAATTGGATCCACAGAATCGCTCGGTTATTCGCGGGGATGAAACAGTTCCTTTAACAAAACGTGAG
TTTGATTTGTTATCTGCTTTGATGTCTAACATGAACCGTGTCATGACACGTGAAGAATTATTAAATCTTGTCTGGAAGTA
TGATGAAGCTGTAGAAACAAATGTTGTTGATGTCTACATTCGTTATCTTCGTGGCAAGATTGATGTCTCTGGTAAAGAAT
CATACATTCAAACTGTCCGTGGTATGGGTTATGTCATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A345VI01

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

80.786

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

67.544

99.563

0.672
  vicR Streptococcus mutans UA159

44.156

100

0.445
  micA Streptococcus pneumoniae Cp1015

42.308

100

0.432

Multiple sequence alignment