Detailed information NTG1021824

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: U2F28_RS13905
• Genome accession: NZ_CP160635
• Coordinates: 2747714..2748601 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN44
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2742714..2753601

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2F28_RS13875 (U2F28_013875)	-	2742733..2742825 (+)	93	WP_010956583.1	hypothetical protein	-
U2F28_RS13880 (U2F28_013880)	-	2742933..2743430 (-)	498	WP_001065268.1	glutathione peroxidase	-
U2F28_RS13885 (U2F28_013885)	-	2743440..2743700 (-)	261	WP_078160755.1	hypothetical protein	-
U2F28_RS13890 (U2F28_013890)	-	2744082..2744195 (-)	114	Protein_2698	hypothetical protein	-
U2F28_RS13895 (U2F28_013895)	-	2744854..2746854 (-)	2001	WP_000776754.1	ABC transporter permease	-
U2F28_RS13900 (U2F28_013900)	-	2746851..2747606 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
U2F28_RS13905 (U2F28_013905)	braS	2747714..2748601 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
U2F28_RS13910 (U2F28_013910)	braR	2748612..2749277 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
U2F28_RS13915 (U2F28_013915)	-	2749303..2749503 (-)	201	WP_000604730.1	hypothetical protein	-
U2F28_RS13920 (U2F28_013920)	-	2749701..2751125 (+)	1425	WP_000953755.1	alkaline phosphatase	-
U2F28_RS13925 (U2F28_013925)	-	2751185..2751286 (-)	102	WP_000731976.1	SE2200 family small protein	-
U2F28_RS13930 (U2F28_013930)	-	2751408..2751863 (-)	456	WP_322412254.1	MarR family winged helix-turn-helix transcriptional regulator	-
U2F28_RS13935 (U2F28_013935)	-	2752108..2752869 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1021824 U2F28_RS13905 WP_000143425.1 2747714..2748601(-) (braS) [Staphylococcus aureus strain BSN44]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1021824 U2F28_RS13905 WP_000143425.1 2747714..2748601(-) (braS) [Staphylococcus aureus strain BSN44]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1