Detailed information NTG1021780

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: U2F24_RS13495
• Genome accession: NZ_CP160634
• Coordinates: 2698460..2699347 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN43
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2693460..2704347

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2F24_RS13465 (U2F24_013465)	-	2693479..2693571 (+)	93	WP_010956583.1	hypothetical protein	-
U2F24_RS13470 (U2F24_013470)	-	2693679..2694176 (-)	498	WP_001065268.1	glutathione peroxidase	-
U2F24_RS13475 (U2F24_013475)	-	2694186..2694446 (-)	261	WP_001791974.1	hypothetical protein	-
U2F24_RS13480 (U2F24_013480)	-	2694828..2694941 (-)	114	Protein_2616	hypothetical protein	-
U2F24_RS13485 (U2F24_013485)	-	2695600..2697600 (-)	2001	WP_000776754.1	ABC transporter permease	-
U2F24_RS13490 (U2F24_013490)	-	2697597..2698352 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
U2F24_RS13495 (U2F24_013495)	braS	2698460..2699347 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
U2F24_RS13500 (U2F24_013500)	braR	2699358..2700023 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
U2F24_RS13505 (U2F24_013505)	-	2700049..2700249 (-)	201	WP_000604730.1	hypothetical protein	-
U2F24_RS13510 (U2F24_013510)	-	2700447..2701871 (+)	1425	WP_000953755.1	alkaline phosphatase	-
U2F24_RS13515 (U2F24_013515)	-	2701931..2702032 (-)	102	WP_000731976.1	SE2200 family small protein	-
U2F24_RS13520 (U2F24_013520)	-	2702154..2702609 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
U2F24_RS13525 (U2F24_013525)	-	2702854..2703615 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1021780 U2F24_RS13495 WP_000143425.1 2698460..2699347(-) (braS) [Staphylococcus aureus strain BSN43]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1021780 U2F24_RS13495 WP_000143425.1 2698460..2699347(-) (braS) [Staphylococcus aureus strain BSN43]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1