Detailed information NTG1021775

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: U2F24_RS09980
• Genome accession: NZ_CP160634
• Coordinates: 2008671..2009714 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN43
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2003671..2014714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
U2F24_RS09950 (U2F24_009950)	-	2004092..2005348 (-)	1257	WP_001795108.1	aminopeptidase	-
U2F24_RS09955 (U2F24_009955)	-	2005351..2005551 (-)	201	WP_000180460.1	DUF1128 family protein	-
U2F24_RS09960 (U2F24_009960)	-	2005698..2006162 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
U2F24_RS09965 (U2F24_009965)	-	2006169..2006444 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
U2F24_RS09970 (U2F24_009970)	-	2006722..2007939 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
U2F24_RS09975 (U2F24_009975)	vraR	2008052..2008681 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
U2F24_RS09980 (U2F24_009980)	vraS	2008671..2009714 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
U2F24_RS09985 (U2F24_009985)	liaF	2009711..2010412 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
U2F24_RS09990 (U2F24_009990)	-	2010427..2010813 (-)	387	WP_001110179.1	hypothetical protein	-
U2F24_RS09995 (U2F24_009995)	map	2011030..2011788 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
U2F24_RS10000 (U2F24_010000)	-	2012319..2013305 (+)	987	WP_000999710.1	aromatic acid exporter family protein	-
U2F24_RS10005 (U2F24_010005)	-	2013736..2014149 (-)	414	WP_001557448.1	hypothetical protein	-
U2F24_RS10010 (U2F24_010010)	-	2014178..2014288 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1021775 U2F24_RS09980 WP_001017131.1 2008671..2009714(-) (vraS) [Staphylococcus aureus strain BSN43]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1021775 U2F24_RS09980 WP_001017131.1 2008671..2009714(-) (vraS) [Staphylococcus aureus strain BSN43]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1