Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   U2F24_RS00205 Genome accession   NZ_CP160634
Coordinates   48041..49390 (-) Length   449 a.a.
NCBI ID   WP_031870019.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BSN43     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 39626..54669 48041..49390 within 0


Gene organization within MGE regions


Location: 39626..54669
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  U2F24_RS00165 (U2F24_000165) mecA 39626..41635 (-) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  U2F24_RS00170 (U2F24_000170) - 41732..42718 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  U2F24_RS00175 (U2F24_000175) - 42690..42950 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  U2F24_RS00180 (U2F24_000180) - 42941..44548 (-) 1608 Protein_33 IS1182 family transposase -
  U2F24_RS00185 (U2F24_000185) - 44600..45106 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  U2F24_RS00190 (U2F24_000190) - 45121..45432 (-) 312 WP_000700851.1 DUF960 family protein -
  U2F24_RS00195 (U2F24_000195) - 45519..45869 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  U2F24_RS00200 (U2F24_000200) ccrB 46391..48019 (-) 1629 WP_031870018.1 cassette chromosome recombinase CcrB Machinery gene
  U2F24_RS00205 (U2F24_000205) ccrA 48041..49390 (-) 1350 WP_031870019.1 cassette chromosome recombinase CcrA Machinery gene
  U2F24_RS00210 (U2F24_000210) - 49624..51417 (-) 1794 WP_000195104.1 cassette chromosome replicative helicase -
  U2F24_RS00215 (U2F24_000215) - 51417..51710 (-) 294 WP_001587828.1 cassette chromosome ssDNA-binding protein -
  U2F24_RS00220 (U2F24_000220) - 51945..53084 (+) 1140 Protein_41 IS3 family transposase -
  U2F24_RS00225 (U2F24_000225) - 53155..54669 (-) 1515 WP_001587831.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 52716.33 Da        Isoelectric Point: 9.9693

>NTDB_id=1021741 U2F24_RS00205 WP_031870019.1 48041..49390(-) (ccrA) [Staphylococcus aureus strain BSN43]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYRVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHALFGYEYH
NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRLQKQTKQTSSDNQLKQKINCPCCNATLTNMTVRKKNHILRYYVCPKNMNASRFVCDFKGINAQTFEDKVLEV
CRDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1021741 U2F24_RS00205 WP_031870019.1 48041..49390(-) (ccrA) [Staphylococcus aureus strain BSN43]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAAGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACACAATTAATTCAACAAGGACAATGTGACATATTATGCTGTTATCGTCTTAATAGGTTGCATCGTAAT
TTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATATCGCGTTCATATCTTAAGTGTGCATGATGGTTATTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCTCTTTGGTTACGAATATCAC
AACGGAACATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTACTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATTGCAAAAACAAACCAAACAGACATCTTCGGATAATCAACTCAAACAAAAAATCAA
TTGCCCATGTTGTAATGCAACACTTACAAATATGACCGTTAGAAAAAAGAATCATATATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCACGCTTTGTATGTGATTTCAAAGGCATCAATGCACAAACATTTGAAGATAAAGTATTAGAAGTG
TGCCGAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCTCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATCGCATAA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase (Recombinase)

(169-248)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus N315

97.773

100

0.978
  ccrA Staphylococcus aureus COL

73.942

100

0.739

Multiple sequence alignment