Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQM89_RS06055 Genome accession   NZ_LS483382
Coordinates   1155869..1156531 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain NCTC13738     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1150869..1161531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM89_RS06035 (NCTC13738_01206) - 1151483..1151665 (-) 183 WP_076634499.1 hypothetical protein -
  DQM89_RS06040 (NCTC13738_01207) sodA 1151832..1152437 (-) 606 WP_023078860.1 superoxide dismutase SodA -
  DQM89_RS06045 (NCTC13738_01208) holA 1152534..1153574 (-) 1041 WP_011888795.1 DNA polymerase III subunit delta -
  DQM89_RS06050 (NCTC13738_01209) comEC/celB 1153645..1155888 (-) 2244 WP_076634500.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQM89_RS06055 (NCTC13738_01210) comEA/celA/cilE 1155869..1156531 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  DQM89_RS06060 (NCTC13738_01211) - 1156731..1157471 (-) 741 WP_168643124.1 lysophospholipid acyltransferase family protein -
  DQM89_RS06065 (NCTC13738_01212) - 1157589..1158365 (+) 777 WP_023078849.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQM89_RS06070 (NCTC13738_01213) - 1158355..1158633 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  DQM89_RS06075 (NCTC13738_01214) - 1158657..1160657 (-) 2001 WP_076634502.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=1021709 DQM89_RS06055 WP_002995626.1 1155869..1156531(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC13738]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1021709 DQM89_RS06055 WP_002995626.1 1155869..1156531(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC13738]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405