Detailed information NTG1021527

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: V5118_RS09410
• Genome accession: NZ_CP160483
• Coordinates: 1894045..1895088 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN38-MSSA1
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1889045..1900088

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5118_RS09380 (V5118_009380)	-	1889467..1890723 (-)	1257	WP_001793428.1	aminopeptidase	-
V5118_RS09385 (V5118_009385)	-	1890726..1890926 (-)	201	WP_000180463.1	DUF1128 family protein	-
V5118_RS09390 (V5118_009390)	-	1891073..1891537 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
V5118_RS09395 (V5118_009395)	-	1891544..1891819 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
V5118_RS09400 (V5118_009400)	-	1892097..1893314 (+)	1218	WP_337259125.1	YihY/virulence factor BrkB family protein	-
V5118_RS09405 (V5118_009405)	vraR	1893426..1894055 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
V5118_RS09410 (V5118_009410)	vraS	1894045..1895088 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
V5118_RS09415 (V5118_009415)	liaF	1895085..1895786 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
V5118_RS09420 (V5118_009420)	-	1895801..1896187 (-)	387	WP_001110179.1	hypothetical protein	-
V5118_RS09425 (V5118_009425)	map	1896404..1897162 (-)	759	WP_000636144.1	type I methionyl aminopeptidase	-
V5118_RS09430 (V5118_009430)	-	1897693..1898679 (+)	987	WP_031811349.1	aromatic acid exporter family protein	-
V5118_RS09435 (V5118_009435)	-	1899169..1899582 (-)	414	WP_001549145.1	hypothetical protein	-
V5118_RS09440 (V5118_009440)	-	1899611..1899721 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1021527 V5118_RS09410 WP_001017131.1 1894045..1895088(-) (vraS) [Staphylococcus aureus strain BSN38-MSSA1]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1021527 V5118_RS09410 WP_001017131.1 1894045..1895088(-) (vraS) [Staphylococcus aureus strain BSN38-MSSA1]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1