Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DQM54_RS10265 Genome accession   NZ_LS483375
Coordinates   2069731..2071674 (-) Length   647 a.a.
NCBI ID   WP_111724231.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2064731..2076674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS10235 (NCTC3165_02036) - 2066237..2066647 (+) 411 WP_111724227.1 helix-turn-helix domain-containing protein -
  DQM54_RS10240 (NCTC3165_02037) - 2066698..2067357 (-) 660 WP_111724228.1 CPBP family intramembrane glutamic endopeptidase -
  DQM54_RS10245 (NCTC3165_02038) - 2067362..2067916 (-) 555 WP_111724229.1 DNA-3-methyladenine glycosylase I -
  DQM54_RS10250 (NCTC3165_02039) ruvA 2067926..2068519 (-) 594 WP_111724230.1 Holliday junction branch migration protein RuvA Machinery gene
  DQM54_RS10255 (NCTC3165_02040) - 2068687..2069190 (+) 504 WP_111724322.1 helix-turn-helix domain-containing protein -
  DQM54_RS10260 - 2069174..2069695 (+) 522 Protein_1968 RDD family protein -
  DQM54_RS10265 (NCTC3165_02042) hexB 2069731..2071674 (-) 1944 WP_111724231.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQM54_RS10270 (NCTC3165_02043) - 2071859..2072299 (+) 441 WP_061599763.1 LytTR family DNA-binding domain-containing protein -
  DQM54_RS10275 (NCTC3165_02044) - 2072296..2072766 (+) 471 WP_111724232.1 DUF3021 family protein -
  DQM54_RS10280 (NCTC3165_02045) hexA 2072815..2075358 (-) 2544 WP_111724233.1 DNA mismatch repair protein MutS Machinery gene
  DQM54_RS10285 (NCTC3165_02046) argR 2075537..2075974 (-) 438 WP_008809983.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 73391.52 Da        Isoelectric Point: 5.0266

>NTDB_id=1021341 DQM54_RS10265 WP_111724231.1 2069731..2071674(-) (hexB) [Streptococcus gordonii strain NCTC3165]
MSKIIELPEILANQIAAGEVIERPSSVVKELVENSIDAGASQITIEIEEAGLKTIQVTDNGEGIDHEDVPLALRRHATSK
IKKQADLFRIRTLGFRGEAIPSIASVSRFTIETATENGQHGTLLVAQGGEIEEHEPTSSPVGTKIKIEDLFFNTPARLKY
MKSQQAELSHIVDVINRLSLAHPEVAFTLISDGREMTRTAGSGNLRQAIAGIYGLATAKKMVEISASDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVINIQIDPYLADVNVHPTKQEVRISKERELMALISQ
AIATSLKEQDLIPDALENLAKSTVKRATKPEQTSLPLKENRLYYDKERNDFFLKPQVAEQQISFEESAEPIHEAIDEKAE
PQPTSVKFAERRPASYDQLDHPELDQVSLERAVDKLEQEEKSSFPELEYFGQMHGTYLFAQGKGGLYIIDQHAAQERVKY
EYYREKIGDVDNSQQQLLVPYIFEFPADDMLRIKQRMELLEDAGIFLEEYGANQFILREHPIWFKEEEIEAGIYEMCDML
LLTKEVSIKKYRAELAIMMSCKRSIKANHSLDDYSARDLLFQLSQCDNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRELGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=1021341 DQM54_RS10265 WP_111724231.1 2069731..2071674(-) (hexB) [Streptococcus gordonii strain NCTC3165]
ATGTCAAAAATTATCGAACTTCCAGAAATTCTAGCCAATCAGATTGCGGCTGGTGAGGTCATTGAGCGGCCCAGTAGCGT
GGTCAAGGAGCTAGTGGAAAATTCAATTGATGCGGGTGCAAGCCAGATTACCATCGAAATCGAGGAGGCTGGACTCAAGA
CTATCCAGGTGACAGATAATGGTGAGGGCATAGATCACGAAGATGTCCCTCTGGCCCTTCGCCGCCATGCTACCAGTAAA
ATCAAGAAACAGGCGGATCTCTTTCGGATTCGGACACTGGGTTTTCGTGGCGAGGCCATTCCTTCCATTGCTTCTGTATC
GCGTTTTACCATTGAGACTGCAACAGAAAATGGCCAGCACGGGACTTTGCTAGTTGCCCAAGGCGGTGAGATAGAAGAGC
ACGAGCCTACCAGCAGTCCAGTGGGAACGAAAATCAAGATAGAAGATCTTTTCTTCAATACTCCCGCCCGGCTCAAGTAT
ATGAAGAGCCAGCAGGCTGAGCTGTCCCATATCGTTGATGTGATTAATCGGCTCAGTCTGGCCCATCCGGAAGTAGCTTT
CACCCTTATCAGTGACGGCCGCGAAATGACACGGACTGCCGGCAGTGGCAATCTGCGTCAGGCTATTGCAGGCATCTATG
GTCTGGCAACAGCCAAGAAAATGGTGGAAATCTCTGCTTCAGATCTGGACTTTGAAGTGAGCGGCTATGTCAGTCTGCCT
GAACTGACTCGCGCGAATCGGAATTATATTACGATTCTCATTAACGGCCGCTATATCAAGAATTTCCTGCTCAATCGTGC
TATTTTGGACGGCTACGGCAGCAAGCTTATGGTAGGCCGCTTTCCACTAGCAGTCATCAATATCCAGATTGATCCCTATC
TGGCCGATGTCAATGTCCATCCGACCAAGCAAGAGGTGAGGATTTCTAAAGAGCGCGAACTCATGGCCTTGATTTCGCAA
GCCATTGCGACCAGTCTCAAGGAGCAAGACCTTATCCCAGATGCTTTGGAAAATCTAGCCAAATCAACTGTTAAGCGTGC
GACTAAACCCGAACAGACCAGTCTTCCTCTGAAAGAAAATCGCCTCTACTACGATAAGGAGCGGAATGACTTCTTCCTTA
AGCCACAAGTGGCCGAGCAGCAAATATCCTTTGAAGAATCAGCGGAGCCTATTCATGAAGCGATAGATGAAAAAGCAGAA
CCGCAACCGACTTCGGTCAAATTTGCAGAGAGAAGGCCGGCCAGCTATGACCAGTTAGACCATCCAGAGCTAGACCAGGT
CAGTCTGGAGCGGGCTGTAGATAAGTTGGAACAAGAAGAGAAGTCAAGCTTCCCAGAGTTAGAATATTTCGGTCAGATGC
ATGGCACCTATCTCTTTGCTCAGGGCAAGGGTGGCCTTTACATTATTGACCAGCATGCTGCCCAAGAGCGGGTCAAGTAT
GAGTATTATCGGGAGAAGATTGGAGATGTGGACAATAGCCAGCAGCAGCTCTTAGTGCCCTATATCTTTGAATTTCCAGC
GGACGATATGCTGCGAATTAAGCAGCGGATGGAGCTGTTAGAAGATGCAGGCATCTTTTTAGAAGAGTACGGAGCCAACC
AGTTTATCCTCCGTGAGCACCCCATTTGGTTCAAGGAAGAGGAGATTGAGGCCGGCATCTATGAAATGTGTGATATGCTT
CTCCTGACCAAGGAAGTCTCCATCAAGAAATATCGAGCAGAGCTAGCTATTATGATGAGTTGCAAACGCTCCATCAAGGC
CAATCACAGTCTGGATGACTACTCTGCGCGTGACTTGCTCTTTCAGCTGTCCCAGTGTGACAATCCTTATAACTGCCCAC
ACGGCCGGCCGGTCTTGGTTAACTTTACCAAGTCGGATATGGAAAAAATGTTCCGCCGCATTCAGGAAAATCATACTAGC
CTGCGGGAGTTAGGGAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(449-591)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

77.573

100

0.781