Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   AB1F71_RS06485 Genome accession   NZ_CP160386
Coordinates   1326951..1327844 (+) Length   297 a.a.
NCBI ID   WP_002262721.1    Uniprot ID   A0A090B2L0
Organism   Streptococcus mutans strain UA159 ykuR deletion     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1321951..1332844
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB1F71_RS06465 (AB1F71_06465) - 1323914..1324042 (-) 129 WP_002262718.1 hypothetical protein -
  AB1F71_RS06470 (AB1F71_06470) - 1324077..1324307 (-) 231 WP_002282891.1 hypothetical protein -
  AB1F71_RS06475 (AB1F71_06475) - 1324437..1326188 (-) 1752 WP_002262719.1 GbpC/Spa domain-containing protein -
  AB1F71_RS06480 (AB1F71_06480) - 1326351..1326636 (-) 286 Protein_1246 helix-turn-helix transcriptional regulator -
  AB1F71_RS06485 (AB1F71_06485) irvR 1326951..1327844 (+) 894 WP_002262721.1 LexA family transcriptional regulator IrvR Regulator
  AB1F71_RS06490 (AB1F71_06490) - 1328513..1328890 (-) 378 WP_002263544.1 type II toxin-antitoxin system HicB family antitoxin -
  AB1F71_RS06495 (AB1F71_06495) - 1328908..1329099 (-) 192 WP_002263545.1 type II toxin-antitoxin system HicA family toxin -
  AB1F71_RS06500 (AB1F71_06500) csn2 1329196..1329858 (-) 663 WP_002263546.1 type II-A CRISPR-associated protein Csn2 -
  AB1F71_RS06505 (AB1F71_06505) cas2 1329848..1330192 (-) 345 WP_002263547.1 CRISPR-associated endonuclease Cas2 -
  AB1F71_RS06510 (AB1F71_06510) cas1 1330189..1331055 (-) 867 WP_002352326.1 type II CRISPR-associated endonuclease Cas1 -

Sequence

Protein


Download         Length: 297 a.a.        Molecular weight: 33651.40 Da        Isoelectric Point: 6.7038

>NTDB_id=1020681 AB1F71_RS06485 WP_002262721.1 1326951..1327844(+) (irvR) [Streptococcus mutans strain UA159 ykuR deletion]
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFA
SKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTI
IHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKT
KAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT

Nucleotide


Download         Length: 894 bp        

>NTDB_id=1020681 AB1F71_RS06485 WP_002262721.1 1326951..1327844(+) (irvR) [Streptococcus mutans strain UA159 ykuR deletion]
ATGGGACGCGGTAAATTAACTCCACAAGATTTAGAAGCAATGAAGGCTATTTCTGCCAATCTTCAAAGACTTCTAGCTGA
GAGCGGAATGAAACAATCTCACTTAGCTACTATTCTTAACATTCCTACAAGTAGTCTTAACGAATATGTTAAGGGAAAGA
GTTTGCCAAAAATAGGGAATATTCAAAAAATCGCAGATTACTTTGGTTTACAAAAATCCGATATTGACCCTAGATTTGCA
AGTAAAAAGGACTCTTCTACTCTTGATAAAATTAATCATATTGCCAAACAATTAGAAATGAAGAGACAGATAAAAGTCTT
AGATTTCTGTTACCAACAATCAAAAGAACAAGATGAAACAGCAAGCTTGTCTGCCAGTGATGAAACGACTGAGGATAAAG
TTGCTGACAAATCAAATCATACGCAGTATCAAAAGGTTGTTGATTCTTTTATTGCCAAAGAATTAAACGATCAGACAATT
ATTCATTGGGATAATGTGATAAAAGCTAAGGATTTGTATCAAACCTTTGGACGTCAATACGAAAACATTCAGATTTATGG
TGAAGTTTCAGCTGGTACTGGTATCTGGGTTGGACATGAAAAACAAGAAACCATTAAATACCCAATACCAATTCCAGAAC
ATGATATTGCTCTTATTGTCAATGGTAATAGTATGGAACCTTTATTTTACAACGGTGACGTTATTTTTGTTAAAAAGACT
AAAGCTATCCATCACGGACAAATTATCGTTGTTATTGTAAATAATGAGGCATATGTCAAAAAACTCTACCGAAAAAACAA
AGAAATTCGACTCATCTCATTAAATCCAGATTATGATGACATCATTTTAAAAGAAGATGATACAATTGAAGTCATCGGAA
CGGTCATTACCTAA

Domains

Predicted by InterproScan.

Peptidase S24-like (Peptidase_S24)

(184-296)

Helix-turn-helix (HTH_3)

(22-70)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A090B2L0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

100

100

1

Multiple sequence alignment