Detailed information NTG1020227

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: AB0R72_RS18725
• Genome accession: NZ_CP160229
• Coordinates: 3756929..3758092 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AP46
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3751929..3763092

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB0R72_RS18695 (AB0R72_18700)	-	3752193..3752612 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
AB0R72_RS18700 (AB0R72_18705)	comFC	3752686..3753375 (-)	690	WP_217898730.1	phosphoribosyltransferase family protein	Machinery gene
AB0R72_RS18705 (AB0R72_18710)	-	3753381..3753665 (-)	285	WP_007407481.1	competence protein ComFB	-
AB0R72_RS18710 (AB0R72_18715)	comFA	3753723..3755108 (-)	1386	WP_094032535.1	DEAD/DEAH box helicase	Machinery gene
AB0R72_RS18715 (AB0R72_18720)	-	3755217..3756065 (-)	849	WP_003151387.1	DegV family protein	-
AB0R72_RS18720 (AB0R72_18725)	degU	3756163..3756852 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
AB0R72_RS18725 (AB0R72_18730)	degS	3756929..3758092 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
AB0R72_RS18730 (AB0R72_18735)	-	3758315..3758962 (+)	648	WP_061581228.1	YigZ family protein	-
AB0R72_RS18735 (AB0R72_18740)	-	3758967..3760202 (+)	1236	WP_025285355.1	LCP family protein	-
AB0R72_RS18740 (AB0R72_18745)	-	3760301..3761377 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
AB0R72_RS18745 (AB0R72_18750)	-	3761510..3762706 (-)	1197	WP_094032536.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=1020227 AB0R72_RS18725 WP_007407484.1 3756929..3758092(-) (degS) [Bacillus velezensis strain AP46]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=1020227 AB0R72_RS18725 WP_007407484.1 3756929..3758092(-) (degS) [Bacillus velezensis strain AP46]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951