Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AB0R72_RS06265 Genome accession   NZ_CP160229
Coordinates   1230241..1230897 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain AP46     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1225241..1235897
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB0R72_RS06240 (AB0R72_06240) oppF 1225771..1226688 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  AB0R72_RS06245 (AB0R72_06245) - 1226795..1227982 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  AB0R72_RS06250 (AB0R72_06250) - 1228100..1228678 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  AB0R72_RS06255 (AB0R72_06255) spx 1228856..1229251 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  AB0R72_RS06260 (AB0R72_06260) - 1229309..1229965 (-) 657 WP_007409109.1 TerC family protein -
  AB0R72_RS06265 (AB0R72_06265) mecA 1230241..1230897 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  AB0R72_RS06270 (AB0R72_06270) - 1231047..1232207 (+) 1161 WP_144664086.1 competence protein CoiA family protein -
  AB0R72_RS06275 (AB0R72_06275) pepF 1232435..1234264 (+) 1830 WP_099686889.1 oligoendopeptidase F Regulator
  AB0R72_RS06280 (AB0R72_06280) - 1234301..1234468 (-) 168 WP_003155026.1 hypothetical protein -
  AB0R72_RS06285 (AB0R72_06285) spxH 1234755..1235657 (-) 903 WP_039251990.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1020184 AB0R72_RS06265 WP_003155032.1 1230241..1230897(+) (mecA) [Bacillus velezensis strain AP46]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1020184 AB0R72_RS06265 WP_003155032.1 1230241..1230897(+) (mecA) [Bacillus velezensis strain AP46]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment