Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   DQL29_RS00680 Genome accession   NZ_LS483359
Coordinates   104294..104578 (+) Length   94 a.a.
NCBI ID   WP_002987779.1    Uniprot ID   A0A0H2USY2
Organism   Streptococcus pyogenes strain NCTC12068     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99294..109578
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL29_RS00655 (NCTC12068_00133) - 101240..101605 (+) 366 WP_030126461.1 DUF1033 family protein -
  DQL29_RS00660 (NCTC12068_00134) comGA 101698..102636 (+) 939 WP_002993471.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL29_RS00665 (NCTC12068_00135) comGB 102572..103606 (+) 1035 WP_227875237.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL29_RS00670 (NCTC12068_00136) comGC 103608..103934 (+) 327 WP_011528161.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL29_RS00675 (NCTC12068_00137) comGD 103909..104337 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQL29_RS00680 (NCTC12068_00138) comGE 104294..104578 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  DQL29_RS00685 (NCTC12068_00139) comGF 104571..105005 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL29_RS00690 (NCTC12068_00140) comGG 104989..105315 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  DQL29_RS00695 (NCTC12068_00141) comGH 105413..106366 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  DQL29_RS00700 (NCTC12068_00142) - 106425..107621 (+) 1197 WP_030126459.1 acetate kinase -
  DQL29_RS00705 - 107807..108115 (+) 309 WP_030126458.1 hypothetical protein -
  DQL29_RS00710 (NCTC12068_00143) proC 108198..108968 (-) 771 WP_023078993.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 94 a.a.        Molecular weight: 10672.62 Da        Isoelectric Point: 8.9043

>NTDB_id=1020182 DQL29_RS00680 WP_002987779.1 104294..104578(+) (comGE) [Streptococcus pyogenes strain NCTC12068]
MGIIKKQVKAYIALESMIATGILFSIVILVLSSLQQSQAALTYYRKQQEKLNLALMAVQTRTKEMTLNGCHITILRTDRY
ISIHDDEGEVMKIE

Nucleotide


Download         Length: 285 bp        

>NTDB_id=1020182 DQL29_RS00680 WP_002987779.1 104294..104578(+) (comGE) [Streptococcus pyogenes strain NCTC12068]
GTGGGAATTATCAAAAAACAAGTCAAAGCTTACATAGCCCTTGAAAGTATGATCGCAACAGGCATCCTCTTTAGTATTGT
CATTCTCGTCTTAAGCAGTTTACAGCAGAGTCAGGCTGCTCTAACGTACTATCGAAAGCAGCAAGAAAAGCTTAATCTAG
CCTTGATGGCAGTACAAACTAGAACTAAAGAGATGACATTGAATGGTTGTCATATTACTATTTTACGTACGGATAGATAC
ATTAGTATTCACGATGACGAAGGAGAAGTGATGAAGATTGAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(12-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2USY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Lactococcus lactis subsp. cremoris KW2

38.298

100

0.383