Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQM51_RS04380 Genome accession   NZ_LS483356
Coordinates   816624..817100 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC8230     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 811624..822100
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM51_RS04345 (NCTC8230_00866) - 811762..812373 (+) 612 WP_111713231.1 DUF1366 domain-containing protein -
  DQM51_RS04350 (NCTC8230_00867) - 812385..812657 (+) 273 WP_011017397.1 hypothetical protein -
  DQM51_RS04355 (NCTC8230_00868) - 812654..812881 (+) 228 WP_003058873.1 phage holin -
  DQM51_RS04360 (NCTC8230_00870) - 812998..814332 (+) 1335 WP_015898599.1 GH25 family lysozyme -
  DQM51_RS04365 (NCTC8230_00871) spei 814606..815283 (+) 678 WP_080286815.1 streptococcal pyrogenic exotoxin SpeI -
  DQM51_RS04370 speh 815309..816020 (+) 712 Protein_807 streptococcal pyrogenic exotoxin SpeH -
  DQM51_RS04380 (NCTC8230_00873) mutX 816624..817100 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQM51_RS04385 (NCTC8230_00874) - 817158..818339 (+) 1182 WP_111713232.1 AI-2E family transporter -
  DQM51_RS04390 (NCTC8230_00875) - 818329..819576 (+) 1248 WP_111713233.1 tetratricopeptide repeat protein -
  DQM51_RS04395 (NCTC8230_00876) fbp54 819635..821287 (-) 1653 WP_111713234.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1019967 DQM51_RS04380 WP_002984880.1 816624..817100(+) (mutX) [Streptococcus pyogenes strain NCTC8230]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1019967 DQM51_RS04380 WP_002984880.1 816624..817100(+) (mutX) [Streptococcus pyogenes strain NCTC8230]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAAGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACTTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment