Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQL37_RS04230 Genome accession   NZ_LS483352
Coordinates   790502..790978 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC12052     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 785502..795978
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL37_RS04205 (NCTC12052_00829) - 785543..786331 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  DQL37_RS04210 (NCTC12052_00830) - 786371..787477 (+) 1107 WP_020833434.1 NAD(P)/FAD-dependent oxidoreductase -
  DQL37_RS04215 (NCTC12052_00831) rfbA 787535..788404 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQL37_RS04220 (NCTC12052_00832) - 788404..788997 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQL37_RS04225 (NCTC12052_00833) rfbB 789241..790281 (+) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  DQL37_RS04230 (NCTC12052_00834) mutX 790502..790978 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQL37_RS04235 (NCTC12052_00835) - 791036..792217 (+) 1182 WP_038432925.1 AI-2E family transporter -
  DQL37_RS04240 (NCTC12052_00836) - 792207..793454 (+) 1248 WP_109828679.1 tetratricopeptide repeat protein -
  DQL37_RS04245 (NCTC12052_00837) fbp54 793513..795225 (-) 1713 WP_111685727.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1019683 DQL37_RS04230 WP_002984880.1 790502..790978(+) (mutX) [Streptococcus pyogenes strain NCTC12052]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1019683 DQL37_RS04230 WP_002984880.1 790502..790978(+) (mutX) [Streptococcus pyogenes strain NCTC12052]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703