Detailed information NTG1019495

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: AB0R90_RS18430
• Genome accession: NZ_CP160217
• Coordinates: 3652524..3653687 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain AP52
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3647524..3658687

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB0R90_RS18400 (AB0R90_18400)	-	3647788..3648207 (-)	420	WP_025285352.1	TIGR03826 family flagellar region protein	-
AB0R90_RS18405 (AB0R90_18405)	comFC	3648281..3648970 (-)	690	WP_217898730.1	phosphoribosyltransferase family protein	Machinery gene
AB0R90_RS18410 (AB0R90_18410)	-	3648976..3649260 (-)	285	WP_007407481.1	competence protein ComFB	-
AB0R90_RS18415 (AB0R90_18415)	comFA	3649318..3650703 (-)	1386	WP_094032535.1	DEAD/DEAH box helicase	Machinery gene
AB0R90_RS18420 (AB0R90_18420)	-	3650812..3651660 (-)	849	WP_003151387.1	DegV family protein	-
AB0R90_RS18425 (AB0R90_18425)	degU	3651758..3652447 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
AB0R90_RS18430 (AB0R90_18430)	degS	3652524..3653687 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
AB0R90_RS18435 (AB0R90_18435)	-	3653910..3654557 (+)	648	WP_076424607.1	YigZ family protein	-
AB0R90_RS18440 (AB0R90_18440)	-	3654562..3655782 (+)	1221	WP_012118574.1	LCP family protein	-
AB0R90_RS18445 (AB0R90_18445)	-	3655881..3656957 (-)	1077	WP_003151382.1	glycosyltransferase family 4 protein	-
AB0R90_RS18450 (AB0R90_18450)	-	3657090..3658286 (-)	1197	WP_076424609.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=1019495 AB0R90_RS18430 WP_007407484.1 3652524..3653687(-) (degS) [Bacillus velezensis strain AP52]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=1019495 AB0R90_RS18430 WP_007407484.1 3652524..3653687(-) (degS) [Bacillus velezensis strain AP52]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951